Unrecognized myocardial infarction detected on cardiac magnetic resonance imaging: Association with coronary artery calcium score and cardiovascular risk prediction scores in asymptomatic Asian cohort

To investigate the association between unrecognized myocardial infarction (UMI) assessed with cardiac magnetic resonance (CMR) and coronary artery calcium (CAC) and cardiovascular risk prediction scores in asymptomatic Asian subjects. Total 872 asymptomatic subjects without prior cardiovascular even...

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Published in:PloS one 2018-09, Vol.13 (9), p.e0204040-e0204040
Main Authors: Cha, Min Jae, Kim, Sung Mok, Kim, Yiseul, Kim, Hyun Su, Cho, Soo Jin, Sung, Jidong, Choe, Yeon Hyeon
Format: Article
Language:English
Subjects:
Arteriosclerosis
Atherosclerosis
Biology and Life Sciences
Calcification (ectopic)
Calcium
Cardiovascular diseases
Computed tomography
Confidence intervals
Coronary artery
EKG
Electrocardiography
Gadolinium
Health risks
Heart
Heart attacks
Magnetic resonance
Magnetic resonance imaging
Medical imaging
Medicine and Health Sciences
Myocardial infarction
Physical Sciences
Predictions
Research and Analysis Methods
Resonance
Risk
Studies
Tomography
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Summary:To investigate the association between unrecognized myocardial infarction (UMI) assessed with cardiac magnetic resonance (CMR) and coronary artery calcium (CAC) and cardiovascular risk prediction scores in asymptomatic Asian subjects. Total 872 asymptomatic subjects without prior cardiovascular event (male:female, 817:55; age, 53.88 ± 5.91) who underwent both CMR and CAC scoring CT were included. UMI were accessed and framingham risk score (FRS) and ASCVD (atherosclerotic cardiovascular disease) risk score by ACC/AHA were calculated. Late gadolinium enhancement indicating UMI was noted in 23 of 872 subjects (2.64%), but only three of them showed ECG abnormality (13.04%). Subjects with UMI showed higher CAC scores, FRS, and ASCVD scores than those without UMI (p < .001, p = .011 and p = .024, respectively). The prevalence of UMI differed significantly according to the CAC scores as follows: 1% in CAC = 0 (4/403), 1% in 1 ≤ CAC
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0204040