Adherence to etanercept therapy in rheumatoid arthritis patients during 3 years of follow-up

To determine the percentage non-adherence to etanercept in patients with rheumatoid arthritis during three years of follow-up. During study visits in this prospective cohort study, blood samples were taken to determine serum etanercept concentrations using ELISA and patients were asked if they had m...

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Bibliographic Details
Published in:PloS one 2018-10, Vol.13 (10), p.e0205125-e0205125
Main Authors: Vogelzang, E H, Hebing, R C F, Nurmohamed, M T, van Kuijk, A W R, Kruijff, J W F, l'Ami, M J, Krieckaert, C L M, Wolbink, G
Format: Article
Language:English
Subjects:
Adhesion
Arthritis
Biology and Life Sciences
Cohort analysis
Confidence intervals
Drug dosages
Enzyme-linked immunosorbent assay
Etanercept
Exposure
Immunology
Infections
Medical personnel
Medicine and Health Sciences
Patient compliance
Patients
Physicians
Research and Analysis Methods
Rheumatism
Rheumatoid arthritis
Rheumatology
Studies
Therapy
TNF inhibitors
Tumor necrosis factor-TNF
Urinary tract infections
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Summary:To determine the percentage non-adherence to etanercept in patients with rheumatoid arthritis during three years of follow-up. During study visits in this prospective cohort study, blood samples were taken to determine serum etanercept concentrations using ELISA and patients were asked if they had missed an etanercept dose, at which date and for what reason. Non-adherence was defined as serum etanercept concentration
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0205125