Dermoscopy of venous lake on the lips: A comparative study with labial melanotic macule

• Published in: PloS one 2018-10, Vol.13 (10), p.e0206768-e0206768
• Main Authors: Lee, Ji Su, Mun, Je-Ho
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Archives & records; Biology and Life Sciences; Coloration; Comparative studies; Dermatology; Dermoscopy; Diagnosis; Diagnosis, Differential; Earth Sciences; Ecology and Environmental Sciences; Engineering and Technology; Female; Geriatrics; Globules; Hemangioma - diagnostic imaging; Humans; Lakes; Lasers; Lesions; Lip - diagnostic imaging; Lip cancer; Lip Neoplasms - diagnostic imaging; Male; Medical diagnosis; Medicine and Health Sciences; Melanoma; Melanoma - diagnostic imaging; Melanoma, Cutaneous Malignant; Microscope and microscopy; Microscopy; Middle Aged; Morphology; Older people; Oral cancer; People and Places; Retrospective Studies; Skin cancer; Skin Neoplasms - diagnostic imaging; Studies; Surgery; Young Adult
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0206768

Venous lake (VL) is a common vascular tumor occurring on the lips in the elderly. VL is sometimes difficult to distinguish from melanotic lesions such as labial melanotic macule (LMM) or oral malignant melanoma. However, the dermoscopic features of VL have not been sufficiently established in the literature. This study was aimed at investigating the dermoscopic features of VL on the lips, and to compare the dermoscopic features of VL with those of LMM. We retrospectively investigated the dermoscopic findings of histopathologically proven cases of VL and LMM. The structureless pattern (78.6%) and globules/clods (42.9%) were the common patterns in VL cases. Purple was the most frequent color (78.6%), followed by red (42.9%) and blue (42.9%). The structureless pattern (p = 0.003) and the colors purple (p = 0.000), red (p = 0.003), and blue (p = 0.018) were significantly more common in VL than in LMM. In contrast, lines (p = 0.000) and dots (p = 0.044) as patterns, and brown (p = 0.000) and gray (p = 0.044) colors were significantly more frequent in LMM. White structures were more common in VL than in LMM (p = 0.001). Structureless patterns or globules/clods with purple, red, or blue coloration can be useful findings when differentiating VLs from LMM on dermoscopy. Therefore, dermoscopic evaluation is a helpful noninvasive ancillary tool in the diagnosis of VL.