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Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects

Pathophysiological background in different phenotypes of nonalcoholic fatty liver disease (NAFLD) remains to be elucidated. The aim was to investigate the association between fecal and blood microbiota profiles and the presence of NAFLD in obese versus lean subjects. Demographic and clinical data we...

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Bibliographic Details
Published in:PloS one 2019-03, Vol.14 (3), p.e0213692
Main Authors: Yun, Yeojun, Kim, Han-Na, Lee, Eun-Ju, Ryu, Seungho, Chang, Yoosoo, Shin, Hocheol, Kim, Hyung-Lae, Kim, Tae Hun, Yoo, Kwon, Kim, Hwi Young
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Language:English
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Summary:Pathophysiological background in different phenotypes of nonalcoholic fatty liver disease (NAFLD) remains to be elucidated. The aim was to investigate the association between fecal and blood microbiota profiles and the presence of NAFLD in obese versus lean subjects. Demographic and clinical data were reviewed in 268 health checkup examinees, whose fecal and blood samples were available for microbiota analysis. NAFLD was diagnosed with ultrasonography, and subjects with NAFLD were further categorized as obese (body mass index (BMI) ≥25) or lean (BMI
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0213692