The effect of cadmium exposition on the structure and mechanical properties of rat incisors

Alterations in the structure and mechanical properties of teeth in adult Wistar rats exposed to cadmium were investigated. Analyses were conducted on two sets of incisors from female and male specimens, that were intoxicated with cadmium (n = 12) or belonged to the control (n = 12). The cadmium grou...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2019-04, Vol.14 (4), p.e0215370
Main Authors: Świetlicka, Izabela, Tomaszewska, Ewa, Muszyński, Siemowit, Valverde Piedra, Jose Luis, Świetlicki, Michał, Prószyński, Adam, Cieślak, Krystian, Wiącek, Dariusz, Szymańczyk, Sylwia, Kamiński, Daniel
Format: Article
Language:English
Subjects:
Animals
Applied physics
Biology and Life Sciences
Biomechanical Phenomena
Biophysics
Cadmium
Cadmium - administration & dosage
Cadmium - pharmacokinetics
Cadmium - toxicity
Cadmium chloride
Crystallization
Crystals
Dental enamel
Dental Enamel - drug effects
Dental Enamel - pathology
Dental Enamel - physiopathology
Dental research
Drinking water
Durapatite - chemistry
Durapatite - metabolism
Enamel
Female
Gender differences
Hardness - drug effects
Health aspects
Hydroxyapatite
Hydroxyapatites
Incisor - drug effects
Incisor - pathology
Incisor - physiopathology
Incisors
Life sciences
Male
Males
Mechanical engineering
Mechanical properties
Medical research
Medicine and Health Sciences
Metabolism
Microscopy
Microscopy, Atomic Force
Microscopy, Electron, Scanning
Minerals - metabolism
Morphology
Physical properties
Physical Sciences
Physiological aspects
Physiology
Proteins
Rats
Rats, Wistar
Research and Analysis Methods
Structure
Teeth
Toxicology
Trace elements
Veterinary medicine
Water
X-Ray Diffraction
Zinc
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473
cites cdi_FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473
container_end_page
container_issue 4
container_start_page e0215370
container_title PloS one
container_volume 14
creator Świetlicka, Izabela
Tomaszewska, Ewa
Muszyński, Siemowit
Valverde Piedra, Jose Luis
Świetlicki, Michał
Prószyński, Adam
Cieślak, Krystian
Wiącek, Dariusz
Szymańczyk, Sylwia
Kamiński, Daniel
description Alterations in the structure and mechanical properties of teeth in adult Wistar rats exposed to cadmium were investigated. Analyses were conducted on two sets of incisors from female and male specimens, that were intoxicated with cadmium (n = 12) or belonged to the control (n = 12). The cadmium group was administered with CdCl2 dissolved in drinking water with a dose of 4mg/kgbw for 10 weeks. The oral intake of cadmium by adult rats led to the range of structural changes in enamel morphology and its mechanical features. A significant increase of cadmium levels in the teeth in comparison to the control, a slight shift in the colour and reduction of pigmented enamel length, higher surface irregularity, a decrease of hydroxyapatite crystals size in the c-axis and simultaneous increase in pigmented enamel hardness were observed. The extent of these changes was sex-dependent and was more pronounced in males.
doi_str_mv 10.1371/journal.pone.0215370
format article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2209404014</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A582174510</galeid><doaj_id>oai_doaj_org_article_9328f9a4de6b4da68e57efd7f9666bba</doaj_id><sourcerecordid>A582174510</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473</originalsourceid><addsrcrecordid>eNqNk9-L1DAQx4so3nn6H4gWBNGHXfOjTdoX4Tj8sXBwoKcvPoQ0mexmaZuapHL-96Zu79jKPUgCCclnvpOZzGTZc4zWmHL8bu9G38t2Pbge1ojgknL0IDvFNSUrRhB9eLQ_yZ6EsEeopBVjj7MTimpekaI6zX5c7yAHY0DF3JlcSd3ZscvhZnDBRuv6PM2YmBD9qOLoIZe9zjtQO9lbJdt88G4AHy2EScDLmNte2eB8eJo9MrIN8Gxez7JvHz9cX3xeXV592lycX64Uq0lcmUY1AKVGlOnGaCibxtQK81ITLbmhFVdQg0KkIdhQICXihCuMFG8IgYLTs-zlQXdoXRBzXoIgBNUFKhAuErE5ENrJvRi87aT_LZy04u-B81shUwiqBZFSVplaFhpYU2jJKig5GM1NzRhrGpm03s_exqYDraCPXrYL0eVNb3di634JVjBMapwE3swC3v0cIUTR2aCgbWUPbjy8u6xrhmlCX_2D3h_dTG1lCsD2xiW_ahIV52VFMC9KjBK1vodKQ0NnVSoiY9P5wuDtwiAxEW7iVo4hiM3XL__PXn1fsq-P2B3INu6Ca8ep2sISLA6g8i4ED-YuyRiJqQdusyGmHhBzDySzF8cfdGd0W_T0D83dAw8</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2209404014</pqid></control><display><type>article</type><title>The effect of cadmium exposition on the structure and mechanical properties of rat incisors</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>PMC (PubMed Central)</source><creator>Świetlicka, Izabela ; Tomaszewska, Ewa ; Muszyński, Siemowit ; Valverde Piedra, Jose Luis ; Świetlicki, Michał ; Prószyński, Adam ; Cieślak, Krystian ; Wiącek, Dariusz ; Szymańczyk, Sylwia ; Kamiński, Daniel</creator><contributor>Kupczik, Kornelius</contributor><creatorcontrib>Świetlicka, Izabela ; Tomaszewska, Ewa ; Muszyński, Siemowit ; Valverde Piedra, Jose Luis ; Świetlicki, Michał ; Prószyński, Adam ; Cieślak, Krystian ; Wiącek, Dariusz ; Szymańczyk, Sylwia ; Kamiński, Daniel ; Kupczik, Kornelius</creatorcontrib><description>Alterations in the structure and mechanical properties of teeth in adult Wistar rats exposed to cadmium were investigated. Analyses were conducted on two sets of incisors from female and male specimens, that were intoxicated with cadmium (n = 12) or belonged to the control (n = 12). The cadmium group was administered with CdCl2 dissolved in drinking water with a dose of 4mg/kgbw for 10 weeks. The oral intake of cadmium by adult rats led to the range of structural changes in enamel morphology and its mechanical features. A significant increase of cadmium levels in the teeth in comparison to the control, a slight shift in the colour and reduction of pigmented enamel length, higher surface irregularity, a decrease of hydroxyapatite crystals size in the c-axis and simultaneous increase in pigmented enamel hardness were observed. The extent of these changes was sex-dependent and was more pronounced in males.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0215370</identifier><identifier>PMID: 30978248</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Animals ; Applied physics ; Biology and Life Sciences ; Biomechanical Phenomena ; Biophysics ; Cadmium ; Cadmium - administration &amp; dosage ; Cadmium - pharmacokinetics ; Cadmium - toxicity ; Cadmium chloride ; Crystallization ; Crystals ; Dental enamel ; Dental Enamel - drug effects ; Dental Enamel - pathology ; Dental Enamel - physiopathology ; Dental research ; Drinking water ; Durapatite - chemistry ; Durapatite - metabolism ; Enamel ; Female ; Gender differences ; Hardness - drug effects ; Health aspects ; Hydroxyapatite ; Hydroxyapatites ; Incisor - drug effects ; Incisor - pathology ; Incisor - physiopathology ; Incisors ; Life sciences ; Male ; Males ; Mechanical engineering ; Mechanical properties ; Medical research ; Medicine and Health Sciences ; Metabolism ; Microscopy ; Microscopy, Atomic Force ; Microscopy, Electron, Scanning ; Minerals - metabolism ; Morphology ; Physical properties ; Physical Sciences ; Physiological aspects ; Physiology ; Proteins ; Rats ; Rats, Wistar ; Research and Analysis Methods ; Structure ; Teeth ; Toxicology ; Trace elements ; Veterinary medicine ; Water ; X-Ray Diffraction ; Zinc</subject><ispartof>PloS one, 2019-04, Vol.14 (4), p.e0215370</ispartof><rights>COPYRIGHT 2019 Public Library of Science</rights><rights>2019 Świetlicka et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 Świetlicka et al 2019 Świetlicka et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473</citedby><cites>FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473</cites><orcidid>0000-0003-1053-0948 ; 0000-0002-4118-6302</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2209404014/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2209404014?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30978248$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kupczik, Kornelius</contributor><creatorcontrib>Świetlicka, Izabela</creatorcontrib><creatorcontrib>Tomaszewska, Ewa</creatorcontrib><creatorcontrib>Muszyński, Siemowit</creatorcontrib><creatorcontrib>Valverde Piedra, Jose Luis</creatorcontrib><creatorcontrib>Świetlicki, Michał</creatorcontrib><creatorcontrib>Prószyński, Adam</creatorcontrib><creatorcontrib>Cieślak, Krystian</creatorcontrib><creatorcontrib>Wiącek, Dariusz</creatorcontrib><creatorcontrib>Szymańczyk, Sylwia</creatorcontrib><creatorcontrib>Kamiński, Daniel</creatorcontrib><title>The effect of cadmium exposition on the structure and mechanical properties of rat incisors</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Alterations in the structure and mechanical properties of teeth in adult Wistar rats exposed to cadmium were investigated. Analyses were conducted on two sets of incisors from female and male specimens, that were intoxicated with cadmium (n = 12) or belonged to the control (n = 12). The cadmium group was administered with CdCl2 dissolved in drinking water with a dose of 4mg/kgbw for 10 weeks. The oral intake of cadmium by adult rats led to the range of structural changes in enamel morphology and its mechanical features. A significant increase of cadmium levels in the teeth in comparison to the control, a slight shift in the colour and reduction of pigmented enamel length, higher surface irregularity, a decrease of hydroxyapatite crystals size in the c-axis and simultaneous increase in pigmented enamel hardness were observed. The extent of these changes was sex-dependent and was more pronounced in males.</description><subject>Animals</subject><subject>Applied physics</subject><subject>Biology and Life Sciences</subject><subject>Biomechanical Phenomena</subject><subject>Biophysics</subject><subject>Cadmium</subject><subject>Cadmium - administration &amp; dosage</subject><subject>Cadmium - pharmacokinetics</subject><subject>Cadmium - toxicity</subject><subject>Cadmium chloride</subject><subject>Crystallization</subject><subject>Crystals</subject><subject>Dental enamel</subject><subject>Dental Enamel - drug effects</subject><subject>Dental Enamel - pathology</subject><subject>Dental Enamel - physiopathology</subject><subject>Dental research</subject><subject>Drinking water</subject><subject>Durapatite - chemistry</subject><subject>Durapatite - metabolism</subject><subject>Enamel</subject><subject>Female</subject><subject>Gender differences</subject><subject>Hardness - drug effects</subject><subject>Health aspects</subject><subject>Hydroxyapatite</subject><subject>Hydroxyapatites</subject><subject>Incisor - drug effects</subject><subject>Incisor - pathology</subject><subject>Incisor - physiopathology</subject><subject>Incisors</subject><subject>Life sciences</subject><subject>Male</subject><subject>Males</subject><subject>Mechanical engineering</subject><subject>Mechanical properties</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Metabolism</subject><subject>Microscopy</subject><subject>Microscopy, Atomic Force</subject><subject>Microscopy, Electron, Scanning</subject><subject>Minerals - metabolism</subject><subject>Morphology</subject><subject>Physical properties</subject><subject>Physical Sciences</subject><subject>Physiological aspects</subject><subject>Physiology</subject><subject>Proteins</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Research and Analysis Methods</subject><subject>Structure</subject><subject>Teeth</subject><subject>Toxicology</subject><subject>Trace elements</subject><subject>Veterinary medicine</subject><subject>Water</subject><subject>X-Ray Diffraction</subject><subject>Zinc</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNk9-L1DAQx4so3nn6H4gWBNGHXfOjTdoX4Tj8sXBwoKcvPoQ0mexmaZuapHL-96Zu79jKPUgCCclnvpOZzGTZc4zWmHL8bu9G38t2Pbge1ojgknL0IDvFNSUrRhB9eLQ_yZ6EsEeopBVjj7MTimpekaI6zX5c7yAHY0DF3JlcSd3ZscvhZnDBRuv6PM2YmBD9qOLoIZe9zjtQO9lbJdt88G4AHy2EScDLmNte2eB8eJo9MrIN8Gxez7JvHz9cX3xeXV592lycX64Uq0lcmUY1AKVGlOnGaCibxtQK81ITLbmhFVdQg0KkIdhQICXihCuMFG8IgYLTs-zlQXdoXRBzXoIgBNUFKhAuErE5ENrJvRi87aT_LZy04u-B81shUwiqBZFSVplaFhpYU2jJKig5GM1NzRhrGpm03s_exqYDraCPXrYL0eVNb3di634JVjBMapwE3swC3v0cIUTR2aCgbWUPbjy8u6xrhmlCX_2D3h_dTG1lCsD2xiW_ahIV52VFMC9KjBK1vodKQ0NnVSoiY9P5wuDtwiAxEW7iVo4hiM3XL__PXn1fsq-P2B3INu6Ca8ep2sISLA6g8i4ED-YuyRiJqQdusyGmHhBzDySzF8cfdGd0W_T0D83dAw8</recordid><startdate>20190412</startdate><enddate>20190412</enddate><creator>Świetlicka, Izabela</creator><creator>Tomaszewska, Ewa</creator><creator>Muszyński, Siemowit</creator><creator>Valverde Piedra, Jose Luis</creator><creator>Świetlicki, Michał</creator><creator>Prószyński, Adam</creator><creator>Cieślak, Krystian</creator><creator>Wiącek, Dariusz</creator><creator>Szymańczyk, Sylwia</creator><creator>Kamiński, Daniel</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-1053-0948</orcidid><orcidid>https://orcid.org/0000-0002-4118-6302</orcidid></search><sort><creationdate>20190412</creationdate><title>The effect of cadmium exposition on the structure and mechanical properties of rat incisors</title><author>Świetlicka, Izabela ; Tomaszewska, Ewa ; Muszyński, Siemowit ; Valverde Piedra, Jose Luis ; Świetlicki, Michał ; Prószyński, Adam ; Cieślak, Krystian ; Wiącek, Dariusz ; Szymańczyk, Sylwia ; Kamiński, Daniel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Animals</topic><topic>Applied physics</topic><topic>Biology and Life Sciences</topic><topic>Biomechanical Phenomena</topic><topic>Biophysics</topic><topic>Cadmium</topic><topic>Cadmium - administration &amp; dosage</topic><topic>Cadmium - pharmacokinetics</topic><topic>Cadmium - toxicity</topic><topic>Cadmium chloride</topic><topic>Crystallization</topic><topic>Crystals</topic><topic>Dental enamel</topic><topic>Dental Enamel - drug effects</topic><topic>Dental Enamel - pathology</topic><topic>Dental Enamel - physiopathology</topic><topic>Dental research</topic><topic>Drinking water</topic><topic>Durapatite - chemistry</topic><topic>Durapatite - metabolism</topic><topic>Enamel</topic><topic>Female</topic><topic>Gender differences</topic><topic>Hardness - drug effects</topic><topic>Health aspects</topic><topic>Hydroxyapatite</topic><topic>Hydroxyapatites</topic><topic>Incisor - drug effects</topic><topic>Incisor - pathology</topic><topic>Incisor - physiopathology</topic><topic>Incisors</topic><topic>Life sciences</topic><topic>Male</topic><topic>Males</topic><topic>Mechanical engineering</topic><topic>Mechanical properties</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Metabolism</topic><topic>Microscopy</topic><topic>Microscopy, Atomic Force</topic><topic>Microscopy, Electron, Scanning</topic><topic>Minerals - metabolism</topic><topic>Morphology</topic><topic>Physical properties</topic><topic>Physical Sciences</topic><topic>Physiological aspects</topic><topic>Physiology</topic><topic>Proteins</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Research and Analysis Methods</topic><topic>Structure</topic><topic>Teeth</topic><topic>Toxicology</topic><topic>Trace elements</topic><topic>Veterinary medicine</topic><topic>Water</topic><topic>X-Ray Diffraction</topic><topic>Zinc</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Świetlicka, Izabela</creatorcontrib><creatorcontrib>Tomaszewska, Ewa</creatorcontrib><creatorcontrib>Muszyński, Siemowit</creatorcontrib><creatorcontrib>Valverde Piedra, Jose Luis</creatorcontrib><creatorcontrib>Świetlicki, Michał</creatorcontrib><creatorcontrib>Prószyński, Adam</creatorcontrib><creatorcontrib>Cieślak, Krystian</creatorcontrib><creatorcontrib>Wiącek, Dariusz</creatorcontrib><creatorcontrib>Szymańczyk, Sylwia</creatorcontrib><creatorcontrib>Kamiński, Daniel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Science (Gale in Context)</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological &amp; Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Meteorological &amp; Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Engineering Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest advanced technologies &amp; aerospace journals</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials science collection</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Świetlicka, Izabela</au><au>Tomaszewska, Ewa</au><au>Muszyński, Siemowit</au><au>Valverde Piedra, Jose Luis</au><au>Świetlicki, Michał</au><au>Prószyński, Adam</au><au>Cieślak, Krystian</au><au>Wiącek, Dariusz</au><au>Szymańczyk, Sylwia</au><au>Kamiński, Daniel</au><au>Kupczik, Kornelius</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of cadmium exposition on the structure and mechanical properties of rat incisors</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2019-04-12</date><risdate>2019</risdate><volume>14</volume><issue>4</issue><spage>e0215370</spage><pages>e0215370-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Alterations in the structure and mechanical properties of teeth in adult Wistar rats exposed to cadmium were investigated. Analyses were conducted on two sets of incisors from female and male specimens, that were intoxicated with cadmium (n = 12) or belonged to the control (n = 12). The cadmium group was administered with CdCl2 dissolved in drinking water with a dose of 4mg/kgbw for 10 weeks. The oral intake of cadmium by adult rats led to the range of structural changes in enamel morphology and its mechanical features. A significant increase of cadmium levels in the teeth in comparison to the control, a slight shift in the colour and reduction of pigmented enamel length, higher surface irregularity, a decrease of hydroxyapatite crystals size in the c-axis and simultaneous increase in pigmented enamel hardness were observed. The extent of these changes was sex-dependent and was more pronounced in males.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>30978248</pmid><doi>10.1371/journal.pone.0215370</doi><tpages>e0215370</tpages><orcidid>https://orcid.org/0000-0003-1053-0948</orcidid><orcidid>https://orcid.org/0000-0002-4118-6302</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1932-6203
ispartof PloS one, 2019-04, Vol.14 (4), p.e0215370
issn 1932-6203
1932-6203
language eng
recordid cdi_plos_journals_2209404014
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PMC (PubMed Central)
subjects Animals
Applied physics
Biology and Life Sciences
Biomechanical Phenomena
Biophysics
Cadmium
Cadmium - administration & dosage
Cadmium - pharmacokinetics
Cadmium - toxicity
Cadmium chloride
Crystallization
Crystals
Dental enamel
Dental Enamel - drug effects
Dental Enamel - pathology
Dental Enamel - physiopathology
Dental research
Drinking water
Durapatite - chemistry
Durapatite - metabolism
Enamel
Female
Gender differences
Hardness - drug effects
Health aspects
Hydroxyapatite
Hydroxyapatites
Incisor - drug effects
Incisor - pathology
Incisor - physiopathology
Incisors
Life sciences
Male
Males
Mechanical engineering
Mechanical properties
Medical research
Medicine and Health Sciences
Metabolism
Microscopy
Microscopy, Atomic Force
Microscopy, Electron, Scanning
Minerals - metabolism
Morphology
Physical properties
Physical Sciences
Physiological aspects
Physiology
Proteins
Rats
Rats, Wistar
Research and Analysis Methods
Structure
Teeth
Toxicology
Trace elements
Veterinary medicine
Water
X-Ray Diffraction
Zinc
title The effect of cadmium exposition on the structure and mechanical properties of rat incisors
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T00%3A32%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20effect%20of%20cadmium%20exposition%20on%20the%20structure%20and%20mechanical%20properties%20of%20rat%20incisors&rft.jtitle=PloS%20one&rft.au=%C5%9Awietlicka,%20Izabela&rft.date=2019-04-12&rft.volume=14&rft.issue=4&rft.spage=e0215370&rft.pages=e0215370-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0215370&rft_dat=%3Cgale_plos_%3EA582174510%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c692t-fbcbee5d036dbfde5bbf9c175d2da7f387ce9ec02b21f3e250727c10c7b22e473%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2209404014&rft_id=info:pmid/30978248&rft_galeid=A582174510&rfr_iscdi=true