Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery

Numerous studies have revealed the role of dietary acid load as a potential risk factor for cardiovascular events and blood pressure. However, its role in predicting the mortality rate in patients underwent coronary artery bypass grafting surgery (CABG) has not been reported. In the current study we...

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Bibliographic Details
Published in:PloS one 2019-10, Vol.14 (10), p.e0223830-e0223830
Main Authors: Abbasalizad Farhangi, Mahdieh, Vajdi, Mahdi, Najafi, Mahdi
Format: Article
Language:English
Subjects:
Acid production
Acid-base status
Acids
Acids - metabolism
Adult
Aged
Aged, 80 and over
Anthropometry
Biology and Life Sciences
Blood pressure
Body Mass Index
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - mortality
Cardiovascular Diseases - pathology
Cardiovascular Diseases - surgery
Coronary artery
Coronary Artery Bypass
Cross-Sectional Studies
Diet
Diet Surveys
Energy Metabolism
Female
Grafting
Health hazards
Health risk assessment
Health risks
Heart surgery
Hematocrit
Humans
Kaplan-Meier Estimate
Male
Medicine and Health Sciences
Middle Aged
Mortality
Mortality risk
Nutrition research
Obesity
Patients
Proportional Hazards Models
Prospective Studies
Quartiles
Rank tests
Risk analysis
Risk factors
Risk reduction
Statistical models
Surgery
Survival
Test procedures
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Summary:Numerous studies have revealed the role of dietary acid load as a potential risk factor for cardiovascular events and blood pressure. However, its role in predicting the mortality rate in patients underwent coronary artery bypass grafting surgery (CABG) has not been reported. In the current study we aimed to evaluate the relationship of dietary acid load and cardio-metabolic risk factors with ten year survival among patients underwent CABG. The current prospective cohort study comprises 454 patients underwent CABG. Anthropometric, clinical and biochemical measurements were performed. Dietary acid load was calculated as either potential renal acid load (PRAL) or net endogenous acid production (NEPA) using the data obtained from a semi-quantitative food frequency questionnaire (FFQ). Survival analysis was performed using Kaplan-Meier method followed by log-rank test. The association between all-cause mortality and study parameters was performed with Cox-proportional hazard model. Patients in the higher PRAL and NEAP quartiles had lower BMI and lower ejection fraction rate (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0223830