Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer

To assess the predictive value of patient characteristics, controlled ovarian stimulation and embryological parameters on the live birth outcome of single euploid frozen-warmed blastocyst transfer (FBT). This was a retrospective cohort study including 707 single FBTs after preimplantation genetic te...

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Bibliographic Details
Published in:PloS one 2020-01, Vol.15 (1), p.e0227619-e0227619
Main Authors: Boynukalin, Fazilet Kubra, Gultomruk, Meral, Cavkaytar, Sabri, Turgut, Emre, Findikli, Necati, Serdarogullari, Munevver, Coban, Onder, Yarkiner, Zalihe, Rubio, Carmen, Bahceci, Mustafa
Format: Article
Language:English
Subjects:
Abortion, Spontaneous
Adult
Aneuploidy
Biology and Life Sciences
Biopsy
Birth Rate
Blastocyst - cytology
Blastocysts
Body mass
Body Mass Index
Body size
Deoxyribonucleic acid
DNA
DNA, Mitochondrial
Embryology
Embryos
Endocrinology
Female
Genetic screening
Humans
Infertility
Laboratories
Live Birth
Male
Medicine and Health Sciences
Middle Aged
Miscarriage
Mitochondrial DNA
Morphology
Parameters
Polymerase chain reaction
Pregnancy
Preimplantation Diagnosis
Regression analysis
Retrospective Studies
Risk Factors
Single Embryo Transfer
Subgroups
Supervision
Trophectoderm
Young Adult
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Summary:To assess the predictive value of patient characteristics, controlled ovarian stimulation and embryological parameters on the live birth outcome of single euploid frozen-warmed blastocyst transfer (FBT). This was a retrospective cohort study including 707 single FBTs after preimplantation genetic testing for aneuploidy (PGT-A) that were performed from October 1, 2015, to January 1, 2018. The effects of patient-, cycle- and embryology-related parameters on the live birth outcome after FBT were assessed. In the subgroup analysis based on live birth, patients who achieved a live birth had a significantly lower body mass index (BMI) than patients who did not achieve a live birth (22.7 (21.5-24.6) kg/m2 vs 27 (24-29.2) kg/m2, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0227619