Risk factors for mild depression in older women with overactive bladder syndrome-A cross sectional study

• Published in: PloS one 2020-01, Vol.15 (1), p.e0227415-e0227415
• Main Authors: Jacomo, Raquel H, Alves, Aline T, Garcia, Patrícia A, da Silva, Marianne L, Matheus, Liana B G, Lorena, Dayanne C R, de Sousa, João B
• Format: Article
• Language: English
• Subjects: Age; Aged; Aged, 80 and over; Anxiety; Anxiety - epidemiology; Anxiety - psychology; Biology and Life Sciences; Bladder; Body mass; Body mass index; Body size; Brazil - epidemiology; Confidence; Cross-Sectional Studies; Depression (Mood disorder); Depression - epidemiology; Depression - psychology; Diabetes mellitus; Disease susceptibility; Exercise; Fecal incontinence; Female; Geriatric depression; Gynecology; Humans; Hypertension; Incontinence; Medical research; Medicine and Health Sciences; Mental depression; Middle Aged; Middle aged women; Multivariate analysis; Older people; Physical activity; Physical therapy; Psychological aspects; Psychotherapy; Quality of life; Questionnaires; Regression analysis; Risk analysis; Risk Factors; Social Sciences; Sociodemographics; Surgery; Surveys and Questionnaires; Syndrome; Urinary Bladder, Overactive - epidemiology; Urinary Bladder, Overactive - psychology; Urogenital system; Womens health
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0227415

Studies demonstrate an association between severe depression and overactive bladder syndrome (OAB). However, mild depression is constantly overlooked. The aim of this study was to evaluate the clinical and sociodemographic factors associated with mild depression in women with OAB. Cross-sectional study involving 241 women over 60 years old in Brasilia, Brazil. All patients were subjected to an interview followed by questionnaires and physical examination. The clinical and sociodemographic variables analyzed were age, body mass index, physical activity level, OAB symptoms, presence of gynecological surgery, fecal incontinence, systemic arterial hypertension, Diabetes Mellitus, anxiety (Beck Anxiety Scale). The Geriatric Depression Scale-15 (GDS-15) was used to identify depression. Univariate logistic regression was used to assess the correlation between mild depression and the variables chosen. Variables with a p-value less than 0.2 were included in the multivariate logistic regression analysis. The level of confidence was set at 95%. 121 volunteers suffered from mild depression. The multivariate analysis demonstrated that gynecological surgery (p < .001) and anxiety (p < .001) are factors associated with mild depression. Older women with a history of gynecological surgery and a GDS-15 score of 2.04 were 1.08 times more likely to develop mild depression compared to older women with no history of gynecological surgery. Anxiety and a history of gynecological surgery are factors that need to be taken into account and may influence the development of mild depression in older women with OAB. Psychological treatment should be considered an important adjunct in the treatment of women with symptoms of Overactive Bladder Syndrome.