Loading…
The benefits of higher LMR for early threatened abortion: A retrospective cohort study
To investigate the relation of inflammation-related parameters and pregnancy outcome in women with the early threatened abortion. 630 women with early threatened abortion were divided into two groups based on the pregnancy outcome. All of them had the blood routine examination before treating. The d...
Saved in:
Published in: | PloS one 2020-04, Vol.15 (4), p.e0231642-e0231642 |
---|---|
Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3 |
---|---|
cites | cdi_FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3 |
container_end_page | e0231642 |
container_issue | 4 |
container_start_page | e0231642 |
container_title | PloS one |
container_volume | 15 |
creator | Feng, Qiu-Ting Chen, Chi Yu, Qing-Ying Chen, Si-Yun Huang, Xian Zhong, Yan-Lan Luo, Song-Ping Gao, Jie |
description | To investigate the relation of inflammation-related parameters and pregnancy outcome in women with the early threatened abortion.
630 women with early threatened abortion were divided into two groups based on the pregnancy outcome. All of them had the blood routine examination before treating. The differences between two groups were analyzed by the Chi-squared test, Student T test, Mann-Whitney U test, Binary Logistic Regression, Marginal Structural Model and Threshold effect analysis.
We found that there is no significant difference in the pregnancy outcome for NLR (OR:0.92, CI95%:0.72, 1.17) and PLR (OR:1.00, CI%:0.99, 1.01). However, a difference had a statistical significance in the pregnancy outcome when LMR less than 2.19 (OR:0.39, CI95%:0.19,0.82).
This study suggested that higher LMR was related to the lower risk of miscarriage in the women with early threatened abortion in a way. |
doi_str_mv | 10.1371/journal.pone.0231642 |
format | article |
fullrecord | <record><control><sourceid>proquest_plos_</sourceid><recordid>TN_cdi_plos_journals_2392432594</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_e9c26de090c04b058eb9f05c3b8755f3</doaj_id><sourcerecordid>2392432594</sourcerecordid><originalsourceid>FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3</originalsourceid><addsrcrecordid>eNptkktr3DAUhU1padK0_6C0gm66makelmx1UQihj8CEQkmyFXpcjT14rKkkB-bfV8k4ISlZSeh-9-ge6VTVe4KXhDXkyyZMcdTDchdGWGLKiKjpi-qYSEYXgmL28tH-qHqT0gZjzlohXldHrOBYtvi4ur7sABkYwfc5oeBR1687iGh18Qf5EBHoOOxR7iLoXCiHtAkx92H8ik5RhBxD2oHN_Q0gG7pSQilPbv-2euX1kODdvJ5UVz--X579Wqx-_zw_O10tLKciL4xtsLONYIK6xnFwWkPrgEheS2F8rY2gQIg10FpMvPCYUKmNJBZaKp1jJ9XHg-5uCEnNT5IUZZLWjHJZF-L8QLigN2oX-62OexV0r-4OQlwrXQzZARRIS4UDLLHFtcG8BSM95paZtuHcs6L1bb5tMltwFsYc9fBE9Gll7Du1DjeqIQ2mnBaBz7NADH8nSFlt-2RhGPQIYbqbm-GaM9oW9NN_6PPu6gNly0ekCP5hGILVbUzuu9RtTNQck9L24bGRh6b7XLB_VkC8VA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2392432594</pqid></control><display><type>article</type><title>The benefits of higher LMR for early threatened abortion: A retrospective cohort study</title><source>PubMed (Medline)</source><source>Publicly Available Content (ProQuest)</source><creator>Feng, Qiu-Ting ; Chen, Chi ; Yu, Qing-Ying ; Chen, Si-Yun ; Huang, Xian ; Zhong, Yan-Lan ; Luo, Song-Ping ; Gao, Jie</creator><creatorcontrib>Feng, Qiu-Ting ; Chen, Chi ; Yu, Qing-Ying ; Chen, Si-Yun ; Huang, Xian ; Zhong, Yan-Lan ; Luo, Song-Ping ; Gao, Jie</creatorcontrib><description>To investigate the relation of inflammation-related parameters and pregnancy outcome in women with the early threatened abortion.
630 women with early threatened abortion were divided into two groups based on the pregnancy outcome. All of them had the blood routine examination before treating. The differences between two groups were analyzed by the Chi-squared test, Student T test, Mann-Whitney U test, Binary Logistic Regression, Marginal Structural Model and Threshold effect analysis.
We found that there is no significant difference in the pregnancy outcome for NLR (OR:0.92, CI95%:0.72, 1.17) and PLR (OR:1.00, CI%:0.99, 1.01). However, a difference had a statistical significance in the pregnancy outcome when LMR less than 2.19 (OR:0.39, CI95%:0.19,0.82).
This study suggested that higher LMR was related to the lower risk of miscarriage in the women with early threatened abortion in a way.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0231642</identifier><identifier>PMID: 32310980</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abortion ; Biology and Life Sciences ; Blood ; Chi-square test ; Chinese medicine ; Cohort analysis ; Hospitals ; Inflammation ; Lymphocytes ; Medical prognosis ; Medicine and Health Sciences ; Miscarriage ; Pregnancy ; Regression analysis ; Regression models ; Statistical analysis ; Statistical tests ; Studies ; Variables ; Womens health</subject><ispartof>PloS one, 2020-04, Vol.15 (4), p.e0231642-e0231642</ispartof><rights>2020 Feng et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 Feng et al 2020 Feng et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3</citedby><cites>FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3</cites><orcidid>0000-0001-5183-0985 ; 0000-0001-6934-6163</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2392432594/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2392432594?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25730,27900,27901,36988,36989,44565,53765,53767,75095</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32310980$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Feng, Qiu-Ting</creatorcontrib><creatorcontrib>Chen, Chi</creatorcontrib><creatorcontrib>Yu, Qing-Ying</creatorcontrib><creatorcontrib>Chen, Si-Yun</creatorcontrib><creatorcontrib>Huang, Xian</creatorcontrib><creatorcontrib>Zhong, Yan-Lan</creatorcontrib><creatorcontrib>Luo, Song-Ping</creatorcontrib><creatorcontrib>Gao, Jie</creatorcontrib><title>The benefits of higher LMR for early threatened abortion: A retrospective cohort study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To investigate the relation of inflammation-related parameters and pregnancy outcome in women with the early threatened abortion.
630 women with early threatened abortion were divided into two groups based on the pregnancy outcome. All of them had the blood routine examination before treating. The differences between two groups were analyzed by the Chi-squared test, Student T test, Mann-Whitney U test, Binary Logistic Regression, Marginal Structural Model and Threshold effect analysis.
We found that there is no significant difference in the pregnancy outcome for NLR (OR:0.92, CI95%:0.72, 1.17) and PLR (OR:1.00, CI%:0.99, 1.01). However, a difference had a statistical significance in the pregnancy outcome when LMR less than 2.19 (OR:0.39, CI95%:0.19,0.82).
This study suggested that higher LMR was related to the lower risk of miscarriage in the women with early threatened abortion in a way.</description><subject>Abortion</subject><subject>Biology and Life Sciences</subject><subject>Blood</subject><subject>Chi-square test</subject><subject>Chinese medicine</subject><subject>Cohort analysis</subject><subject>Hospitals</subject><subject>Inflammation</subject><subject>Lymphocytes</subject><subject>Medical prognosis</subject><subject>Medicine and Health Sciences</subject><subject>Miscarriage</subject><subject>Pregnancy</subject><subject>Regression analysis</subject><subject>Regression models</subject><subject>Statistical analysis</subject><subject>Statistical tests</subject><subject>Studies</subject><subject>Variables</subject><subject>Womens health</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkktr3DAUhU1padK0_6C0gm66makelmx1UQihj8CEQkmyFXpcjT14rKkkB-bfV8k4ISlZSeh-9-ge6VTVe4KXhDXkyyZMcdTDchdGWGLKiKjpi-qYSEYXgmL28tH-qHqT0gZjzlohXldHrOBYtvi4ur7sABkYwfc5oeBR1687iGh18Qf5EBHoOOxR7iLoXCiHtAkx92H8ik5RhBxD2oHN_Q0gG7pSQilPbv-2euX1kODdvJ5UVz--X579Wqx-_zw_O10tLKciL4xtsLONYIK6xnFwWkPrgEheS2F8rY2gQIg10FpMvPCYUKmNJBZaKp1jJ9XHg-5uCEnNT5IUZZLWjHJZF-L8QLigN2oX-62OexV0r-4OQlwrXQzZARRIS4UDLLHFtcG8BSM95paZtuHcs6L1bb5tMltwFsYc9fBE9Gll7Du1DjeqIQ2mnBaBz7NADH8nSFlt-2RhGPQIYbqbm-GaM9oW9NN_6PPu6gNly0ekCP5hGILVbUzuu9RtTNQck9L24bGRh6b7XLB_VkC8VA</recordid><startdate>20200420</startdate><enddate>20200420</enddate><creator>Feng, Qiu-Ting</creator><creator>Chen, Chi</creator><creator>Yu, Qing-Ying</creator><creator>Chen, Si-Yun</creator><creator>Huang, Xian</creator><creator>Zhong, Yan-Lan</creator><creator>Luo, Song-Ping</creator><creator>Gao, Jie</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5183-0985</orcidid><orcidid>https://orcid.org/0000-0001-6934-6163</orcidid></search><sort><creationdate>20200420</creationdate><title>The benefits of higher LMR for early threatened abortion: A retrospective cohort study</title><author>Feng, Qiu-Ting ; Chen, Chi ; Yu, Qing-Ying ; Chen, Si-Yun ; Huang, Xian ; Zhong, Yan-Lan ; Luo, Song-Ping ; Gao, Jie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Abortion</topic><topic>Biology and Life Sciences</topic><topic>Blood</topic><topic>Chi-square test</topic><topic>Chinese medicine</topic><topic>Cohort analysis</topic><topic>Hospitals</topic><topic>Inflammation</topic><topic>Lymphocytes</topic><topic>Medical prognosis</topic><topic>Medicine and Health Sciences</topic><topic>Miscarriage</topic><topic>Pregnancy</topic><topic>Regression analysis</topic><topic>Regression models</topic><topic>Statistical analysis</topic><topic>Statistical tests</topic><topic>Studies</topic><topic>Variables</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Feng, Qiu-Ting</creatorcontrib><creatorcontrib>Chen, Chi</creatorcontrib><creatorcontrib>Yu, Qing-Ying</creatorcontrib><creatorcontrib>Chen, Si-Yun</creatorcontrib><creatorcontrib>Huang, Xian</creatorcontrib><creatorcontrib>Zhong, Yan-Lan</creatorcontrib><creatorcontrib>Luo, Song-Ping</creatorcontrib><creatorcontrib>Gao, Jie</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>Advanced Technologies & Aerospace Database (1962 - current)</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>Biological Sciences</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Feng, Qiu-Ting</au><au>Chen, Chi</au><au>Yu, Qing-Ying</au><au>Chen, Si-Yun</au><au>Huang, Xian</au><au>Zhong, Yan-Lan</au><au>Luo, Song-Ping</au><au>Gao, Jie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The benefits of higher LMR for early threatened abortion: A retrospective cohort study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2020-04-20</date><risdate>2020</risdate><volume>15</volume><issue>4</issue><spage>e0231642</spage><epage>e0231642</epage><pages>e0231642-e0231642</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To investigate the relation of inflammation-related parameters and pregnancy outcome in women with the early threatened abortion.
630 women with early threatened abortion were divided into two groups based on the pregnancy outcome. All of them had the blood routine examination before treating. The differences between two groups were analyzed by the Chi-squared test, Student T test, Mann-Whitney U test, Binary Logistic Regression, Marginal Structural Model and Threshold effect analysis.
We found that there is no significant difference in the pregnancy outcome for NLR (OR:0.92, CI95%:0.72, 1.17) and PLR (OR:1.00, CI%:0.99, 1.01). However, a difference had a statistical significance in the pregnancy outcome when LMR less than 2.19 (OR:0.39, CI95%:0.19,0.82).
This study suggested that higher LMR was related to the lower risk of miscarriage in the women with early threatened abortion in a way.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>32310980</pmid><doi>10.1371/journal.pone.0231642</doi><orcidid>https://orcid.org/0000-0001-5183-0985</orcidid><orcidid>https://orcid.org/0000-0001-6934-6163</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1932-6203 |
ispartof | PloS one, 2020-04, Vol.15 (4), p.e0231642-e0231642 |
issn | 1932-6203 1932-6203 |
language | eng |
recordid | cdi_plos_journals_2392432594 |
source | PubMed (Medline); Publicly Available Content (ProQuest) |
subjects | Abortion Biology and Life Sciences Blood Chi-square test Chinese medicine Cohort analysis Hospitals Inflammation Lymphocytes Medical prognosis Medicine and Health Sciences Miscarriage Pregnancy Regression analysis Regression models Statistical analysis Statistical tests Studies Variables Womens health |
title | The benefits of higher LMR for early threatened abortion: A retrospective cohort study |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-25T09%3A23%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20benefits%20of%20higher%20LMR%20for%20early%20threatened%20abortion:%20A%20retrospective%20cohort%20study&rft.jtitle=PloS%20one&rft.au=Feng,%20Qiu-Ting&rft.date=2020-04-20&rft.volume=15&rft.issue=4&rft.spage=e0231642&rft.epage=e0231642&rft.pages=e0231642-e0231642&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0231642&rft_dat=%3Cproquest_plos_%3E2392432594%3C/proquest_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c526t-bc70dc76362d7d5edaae8de195496bf4ab62e11cbe8c01f6f0129ab91ce829dd3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2392432594&rft_id=info:pmid/32310980&rfr_iscdi=true |