An abdominal spacer that does not require surgical removal and allows drainage of abdominal fluids in patients undergoing carbon ion radiotherapy

Abdominal spacers are useful for maintaining the distance between the target tumors and surrounding tissues, such as the gastrointestinal tract, in patients treated with carbon ion radiotherapy. Surgical intervention to remove the spacers is sometimes necessary because of abdominal infections trigge...

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Published in:PloS one 2020-06, Vol.15 (6), p.e0234471-e0234471
Main Authors: Kubo, Norio, Yokobori, Takehiko, Takahashi, Ryo, Ogawa, Hiroomi, Gombodorj, Navchaa, Ohta, Naoya, Ohno, Tatsuya, Saeki, Hiroshi, Shirabe, Ken, Asao, Takayuki, Crippa, Stefano
Format: Article
Language:English
Subjects:
Abdomen
Biology and Life Sciences
Cancer therapies
Carbon
Care and treatment
Computational fluid dynamics
Drug dosages
Experiments
Gastrointestinal cancer
Gastrointestinal system
Gastrointestinal tract
Hogs
Infections
Intestine
Laparoscopy
Medical equipment
Medicine
Medicine and Health Sciences
Methods
Perforation
Prostate cancer
Radiation therapy
Radiotherapy
Research and Analysis Methods
Spacers
Surgery
Surgical drains
Surgical supplies
Tumors
Wound drainage
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cited_by cdi_FETCH-LOGICAL-c669t-f6e47903928ed54ae2bf8e47ed8a266afe6204df0eb4fd6453fa7b75dd5976493
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creator Kubo, Norio
Yokobori, Takehiko
Takahashi, Ryo
Ogawa, Hiroomi
Gombodorj, Navchaa
Ohta, Naoya
Ohno, Tatsuya
Saeki, Hiroshi
Shirabe, Ken
Asao, Takayuki
Crippa, Stefano
description Abdominal spacers are useful for maintaining the distance between the target tumors and surrounding tissues, such as the gastrointestinal tract, in patients treated with carbon ion radiotherapy. Surgical intervention to remove the spacers is sometimes necessary because of abdominal infections triggered by long-term spacer placement or intestinal perforation. Therefore, spacers that do not require surgical removal and provide effective drainage against abdominal infections are urgently needed. This study aimed to develop a spacer that could be removed non-surgically and one that provides the therapeutic effect of drainage in patients who receive carbon ion radiotherapy for abdominal tumors. A novel fan-shaped spacer was constructed from a film drain that was folded along the trigger line. Simple withdrawal of the trigger line caused the film drain to fold and the holding lines to become free. We performed laparoscopy-assisted insertion with pneumoperitoneum and blind removal of the spacer fourteen times using a porcine model. Saline in the abdominal cavity was effectively aspirated using the spacer. Our novel fan-shaped spacer could be removed safely without surgery and was able to drain fluid effectively from the abdominal cavity.
doi_str_mv 10.1371/journal.pone.0234471
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subjects Abdomen
Biology and Life Sciences
Cancer therapies
Carbon
Care and treatment
Computational fluid dynamics
Drug dosages
Experiments
Gastrointestinal cancer
Gastrointestinal system
Gastrointestinal tract
Hogs
Infections
Intestine
Laparoscopy
Medical equipment
Medicine
Medicine and Health Sciences
Methods
Perforation
Prostate cancer
Radiation therapy
Radiotherapy
Research and Analysis Methods
Spacers
Surgery
Surgical drains
Surgical supplies
Tumors
Wound drainage
title An abdominal spacer that does not require surgical removal and allows drainage of abdominal fluids in patients undergoing carbon ion radiotherapy
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