Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

About the Authors: Cassandra R. Diegel Affiliation: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America Steven Hann Affiliation: Orthopedic Research Labs, Boston Children’s Hospital and D...

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Published in:PLoS genetics 2020-06, Vol.16 (6), p.e1008940-e1008940
Main Authors: Diegel, Cassandra R, Hann, Steven, Ayturk, Ugur M, Hu, Jennifer C.W, Lim, Kyung-Eun, Droscha, Casey J, Madaj, Zachary B, Foxa, Gabrielle E, Izaguirre, Isaac, Robling, Alexander G, Warman, Matthew L, Williams, Bart O
Format: Article
Language:English
Subjects:
Analysis
Anatomy
Animal models
Animal research models
Bioinformatics
Biology
Biology and Life Sciences
Cancer
Children
Computer programs
CRISPR
CRISPR-Cas technology
Formal Comment
Glucose
Glucose tolerance
Hospitals
Insulin
Insulin resistance
Intolerance
Medical schools
Medicine
Medicine and Health Sciences
Metabolism
Mutation
Orthopedics
Osteocalcin
Public policy
Reagents
Research and Analysis Methods
Research validity
Science Policy
Serotonin
Surgery
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Summary:About the Authors: Cassandra R. Diegel Affiliation: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America Steven Hann Affiliation: Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America Ugur M. Ayturk Affiliations Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Musculoskeletal Integrity Program, Hospital for Special Surgery Research Institute, New York, New York, United States of America Jennifer C. W. Hu Affiliation: Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America Kyung-Eun Lim Affiliation: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America Casey J. Droscha Affiliation: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America Zachary B. Madaj Affiliation: Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America Gabrielle E. Foxa Affiliation: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America Isaac Izaguirre Affiliation: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, Michigan, United States of America VAI Vivarium and Transgenics Core ¶Members of the VAI Vivarium and Transgenics Core are listed in the Acknowledgments Affiliation: Vivarium and Transgenics Core, Van Andel Institute, Grand Rapids, Michigan, United States of America Alexander G. Robling Affiliation: Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America Matthew L. Warman Affiliation: Orthopedic Research Labs, Boston Children’s Hospital and Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America Bart O. Williams * E-mail: bart.williams@vai.org Affiliation: Program in Skeletal Disease and Tumor Microenvironment and Center for Cancer and Cell Biology
ISSN:1553-7404
1553-7390
1553-7404
DOI:10.1371/journal.pgen.1008940