Novel genes involved in the genetic architecture of temperament in Brahman cattle

Cattle temperament is a complex and economically relevant trait. The objective of this study was to identify genomic regions and genes associated with cattle temperament. From a Brahman cattle population of 1,370 animals evaluated for temperament traits (Exit velocity-EV, Pen Score-PS, Temperament S...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2020-08, Vol.15 (8), p.e0237825-e0237825
Main Authors: Paredes-Sánchez, Francisco Alejandro, Sifuentes-Rincón, Ana María, Casas, Eduardo, Arellano-Vera, Williams, Parra-Bracamonte, G. Manuel, Riley, David G, Welsh, Thomas H, Randel, Ronald D, Mateescu, Raluca
Format: Article
Language:English
Subjects:
Animal populations
Animal welfare
Animals
Association analysis
Behavior
Biology and Life Sciences
Cattle
Cognitive ability
Evaluation
Females
Genes
Genetic aspects
Genomes
Introns
Laboratory animals
Males
Meat quality
Medicine and Health Sciences
Phenotypes
Population
Quality control
Single-nucleotide polymorphism
Temperament
Weaning
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cattle temperament is a complex and economically relevant trait. The objective of this study was to identify genomic regions and genes associated with cattle temperament. From a Brahman cattle population of 1,370 animals evaluated for temperament traits (Exit velocity-EV, Pen Score-PS, Temperament Score-TS), two groups of temperament-contrasting animals were identified based on their EV-average values ±1/2 standard deviation (SD). To be considered in the calm group, the EV of females ranged between 0.16-1.82 m/s (n = 50) and the EV of males ranged between 0.4-1.56 m/s (n = 48). Females were classified as temperamental if their EV ranged between 3.13-7.66 m/s (n = 46) and males were classified as temperamental if their EV ranged between 3.05-10.83 m/s (n = 45). Selected animals were genotyped using a total of 139,376 SNPs (GGP-HD-150K), evaluated for their association with EV. The Genome-Wide Association analysis (GWAS) identified fourteen SNPs: rs135340276, rs134895560, rs110190635, rs42949831, rs135982573, rs109393235, rs109531929, rs135087545, rs41839733, rs42486577, rs136661522, rs110882543, rs110864071, rs109722627, (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0237825