Incidence of intussusception before and after the introduction of rotavirus vaccine in Korea

Recent studies have reported that after the introduction of rotavirus vaccine the incidence of intussusception did not change among infants, or slightly increased at the age immediately after the first dose. The rotavirus vaccines were introduced in Korea for private market use in 2007-2008. We inve...

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Bibliographic Details
Published in:PloS one 2020-08, Vol.15 (8), p.e0238185-e0238185
Main Authors: Cho, Hye-Kyung, Hwang, Se Hwan, Nam, Hye Na, Han, Kyungdo, Kim, Bongsung, Kong, Insik, Park, Kwangsuk, Lee, Jaeyoung
Format: Article
Language:English
Subjects:
Age
Age groups
Babies
Biology and Life Sciences
Demographic aspects
Disease control
Disease prevention
Health aspects
Health insurance
Hernias
Immunization
Infants
Insurance coverage
Intestinal obstruction
Intussusception
Licenses
Licensing, certification and accreditation
Medical schools
Medicine
Medicine and Health Sciences
Pediatric research
Pediatrics
People and Places
Population
Prevention
Risk factors
Rotavirus
Rotavirus infections
Statistics
Trends
Vaccines
Viral vaccines
Viruses
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Summary:Recent studies have reported that after the introduction of rotavirus vaccine the incidence of intussusception did not change among infants, or slightly increased at the age immediately after the first dose. The rotavirus vaccines were introduced in Korea for private market use in 2007-2008. We investigated the incidence of intussusception before (2002-2006) and after (2009-2015) the vaccine introduction in Korea. We conducted an interrupted time series study that used data from the Korean National Health Insurance database to identify infants (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0238185