Evaluation of the LDBio Aspergillus ICT lateral flow assay for serodiagnosis of allergic bronchopulmonary aspergillosis

Early recognition and diagnosis of allergic bronchopulmonary aspergillosis (ABPA) is critical to improve patient symptoms, and antifungal therapy may prevent or delay progression of bronchiectasis and development of chronic pulmonary aspergillosis. A recently commercialized lateral flow assay (Asper...

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Bibliographic Details
Published in:PloS one 2020-09, Vol.15 (9), p.e0238855-e0238855
Main Authors: Hunter, Elizabeth Stucky, Page, Iain D, Richardson, Malcolm D, Denning, David W
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Allergic bronchopulmonary aspergillosis
Antibodies
Antibodies, Fungal - blood
Antibodies, Fungal - immunology
Antifungal agents
Antigens
Aspergillosis
Aspergillosis, Allergic Bronchopulmonary - diagnosis
Aspergillosis, Allergic Bronchopulmonary - epidemiology
Aspergillosis, Allergic Bronchopulmonary - microbiology
Aspergillus
Aspergillus - immunology
Assaying
Asthma
Bioassay
Biology
Biology and Life Sciences
Bronchiectasis
Bronchoscopy
Commercialization
Correlation analysis
Cystic fibrosis
Diagnosis
Enzymes
Ethics
Evaluation
Female
Fungal infections
Fungicides
Humans
Hypersensitivity
Immunoassay - methods
Immunoglobulin E
Immunoglobulin G
Immunoglobulin G - blood
Immunoglobulin G - immunology
Immunoglobulin M - blood
Immunoglobulin M - immunology
Infections
Male
Medical diagnosis
Medicine
Medicine and Health Sciences
Methods
Middle Aged
Patients
Physiological aspects
Pulmonary aspergillosis
Retrospective Studies
Sensitivity
Serologic tests
Serologic Tests - methods
Serology
Surgery
Thoracic surgery
Thorax
United Kingdom - epidemiology
Young Adult
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Description
Summary:Early recognition and diagnosis of allergic bronchopulmonary aspergillosis (ABPA) is critical to improve patient symptoms, and antifungal therapy may prevent or delay progression of bronchiectasis and development of chronic pulmonary aspergillosis. A recently commercialized lateral flow assay (Aspergillus ICT) (LDBio Diagnostics, Lyons, France) detects Aspergillus-specific antibodies in
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0238855