High plasma soluble levels of the immune checkpoint HLA-G molecule among bodybuilders

Introduction Studies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system. Aim This study aimed to compare the plasma soluble levels of the immune checkpoint HLA-G (sHLA-G) molecule...

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Bibliographic Details
Published in:PloS one 2020-09, Vol.15 (9), p.e0238044-e0238044
Main Authors: Fernandes, Talita M, Puggina, Enrico F, Mendes-Junior, Celso T, de Paula, Milena C, Sonon, Paulin, Donadi, Eduardo A, Fernandes, Ana Paula M
Format: Article
Language:English
Subjects:
Accuracy
Adipose tissue
Age
Antibodies
Antigens
Athletes
Biology and Life Sciences
Body composition
Body fat
Bodybuilders
Bodybuilding
Cytotoxicity
Exercise
Females
Health aspects
Histocompatibility antigen HLA
HLA antigens
Immune checkpoint
Immune response
Immune system
Immunology
Males
Medicine and Health Sciences
Muscles
Nursing
Physical activity
Physical education
Physical fitness
Physical training
Physiological aspects
Software
Statistical analysis
Variance analysis
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Summary:Introduction Studies report that intense physical activity influences the down-regulation of immune function in athletes as well as the interaction between adipose tissue and the immune system. Aim This study aimed to compare the plasma soluble levels of the immune checkpoint HLA-G (sHLA-G) molecule with the fat mass and muscle mass index among 77 bodybuilders and 64 controls. Results The comparisons of the percentage of body fat (%BF) revealed that the groups of male and female bodybuilders showed a statistically significant reduction in the percentage of body fat when compared to their control group, (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0238044