Prevalence of hypertension among adolescents (10-19 years) in India: A systematic review and meta-analysis of cross-sectional studies

Background Despite the well-known short-term and long-term ill effects of elevated blood pressure in children and adolescents, pooled data on its burden among Indian adolescents have not yet been synthesized. Objectives We did a systematic review with meta-analysis to calculate the pooled prevalence...

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Bibliographic Details
Published in:PloS one 2020-10, Vol.15 (10), p.e0239929-e0239929
Main Authors: Daniel, Roy Arokiam, Haldar, Partha, Prasad, Manya, Kant, Shashi, Krishnan, Anand, Gupta, Sanjeev Kumar, Kumar, Rakesh, Choukem, Simeon-Pierre
Format: Article
Language:English
Subjects:
Adolescents
Adults
Blood pressure
Children
Cross-sectional studies
Data collection
Demographic aspects
Diagnostic systems
Distribution
Epidemiology
Health aspects
Heterogeneity
Hypertension
Medicine
Medicine and Health Sciences
Meta-analysis
People and Places
Physical Sciences
Population
Pressure effects
Regression analysis
Regression models
Research and Analysis Methods
Research design
Screening
Search engines
Social Sciences
Statistical analysis
Systematic review
Teenagers
Youth
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Summary:Background Despite the well-known short-term and long-term ill effects of elevated blood pressure in children and adolescents, pooled data on its burden among Indian adolescents have not yet been synthesized. Objectives We did a systematic review with meta-analysis to calculate the pooled prevalence of hypertension among adolescents (10-19 years) in India. Methods We searched PubMed, Embase, Cochrane library, Google Scholar and IndMed, and included cross-sectional studies reporting data on hypertension prevalence among 10 to19 years old and published in English language from their inception till 1.sup.st March 2020. Modified New castle Ottawa scale was used to assess risk of bias based on research design, recruitment strategy, response rate and reliability of outcome determination. A random effects model was used to estimate pooled prevalence, and heterogeneity was assessed using Cochrane's Q statistic test of heterogeneity and I.sup.2 statistic. To explore the heterogeneity, we did a meta-regression, and sub-group analyses based on region, study setting and number of blood pressure readings. Results Out of 25 studies (pooled sample of 27,682 participants) six studies were of high, eighteen of moderate, and one was of low quality. The prevalence of hypertension across studies ranged from 2% to 20.5%, with a pooled estimate of 7.6% (95% CI: 6.1 to 9.1%), I.sup.2 = 96.6% (p-value
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0239929