Sociodemographic features and mortality of individuals on haemodialysis treatment who test positive for SARS-CoV-2: A UK Renal Registry data analysis

Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was...

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Bibliographic Details
Published in:PloS one 2020-10, Vol.15 (10), p.e0241263-e0241263
Main Authors: Savino, Manuela, Casula, Anna, Santhakumaran, Shalini, Pitcher, David, Wong, Esther, Magadi, Winnie, Evans, Katharine M, Benoy-Deeney, Fran, Griffin, James, Plumb, Lucy, Steenkamp, Retha, Nitsch, Dorothea, Medcalf, James
Format: Article
Language:English
Subjects:
Adolescent
Adult
Adults
Age
Aged
Aged, 80 and over
Asian Continental Ancestry Group
Betacoronavirus
Biology and life sciences
Care and treatment
Coronavirus Infections - epidemiology
Coronavirus Infections - ethnology
Coronavirus Infections - mortality
Coronavirus Infections - virology
Coronaviruses
COVID-19
Data Analysis
Data collection
Demographic aspects
Disease transmission
Distribution
England - epidemiology
Female
Health risks
Hemodialysis
Hemodialysis patients
Humans
Kidney diseases
Kidney Failure, Chronic - therapy
Laboratories
Male
Medicine and Health Sciences
Middle Aged
Minority & ethnic groups
Mortality
Pandemics
Patients
Pediatrics
People and places
Pneumonia, Viral - epidemiology
Pneumonia, Viral - ethnology
Pneumonia, Viral - mortality
Pneumonia, Viral - virology
Population
Registries
Renal Dialysis
Retrospective Studies
Risk analysis
Risk Factors
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Supervision
Survival analysis
Wales - epidemiology
Young Adult
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Summary:Kidney disease is a recognised risk factor for poor COVID-19 outcomes. Up to 30 June 2020, the UK Renal Registry (UKRR) collected data for 2,385 in-centre haemodialysis (ICHD) patients with COVID-19 in England and Wales. Overall unadjusted survival at 1 week after date of positive COVID-19 test was 87.5% (95% CI 86.1-88.8%); mortality increased with age, treatment vintage and there was borderline evidence of Asian ethnicity (HR 1.16, 95% CI 0.94-1.44) being associated with higher mortality. Compared to the general population, the relative risk of mortality for ICHD patients with COVID-19 was 45.4 and highest in younger adults. This retrospective cohort study based on UKRR data supports efforts to protect this vulnerable patient group.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0241263