Body mass index trajectories and adiposity rebound during the first 6 years in Korean children: Based on the National Health Information Database, 2008–2015

• Published in: PloS one 2020-10, Vol.15 (10), p.e0232810
• Main Authors: Hwang, Il Tae, Ju, Young-Su, Lee, Hye Jin, Shim, Young Suk, Jeong, Hwal Rim, Kang, Min Jae, Chaput, Jean-Philippe
• Format: Article
• Language: English
• Subjects: Adipose tissue; Biology and Life Sciences; Birth weight; Body mass; Body mass index; Body size; Body weight gain; Breast feeding; Breastfeeding & lactation; Child health; Children; Correlation; Correlation analysis; Demographic aspects; Families & family life; Forecasts and trends; Gestational age; Health aspects; Low birth weight; Males; Medical schools; Medical screening; Medicine; Medicine and Health Sciences; Metabolic syndrome; Nutrition; Obesity; Overweight; Pediatrics; People and Places; Questionnaires; Variables
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0232810

We analyzed the nationwide longitudinal data to explore body mass index (BMI) growth trajectories and the time of adiposity rebound (AR). Personal data of 84,005 subjects born between 2008 and 2012 were obtained from infant health check-ups which were performed at 5, 11, 21, 33, 45, 57, and 69 months. BMI trajectories of each subject were made according to sex and the timing of AR, which was defined as the lowest BMI occurred. Subjects were divided according to birth weight and AR timing as follows: very low birth weight (VLBW), 0.5 kg [less than or equal to] Bwt [less than or equal to] 1.5 kg; low birth weight (LBW), 1.5 kg < Bwt [less than or equal to] 2.5 kg; non-LBW, 2.5 kg < Bwt [less than or equal to] 5.0 kg; very early AR, before 45 months; early AR, at 57 months; and moderate-to-late AR, not until 69 months. Based on this first longitudinal study, the majority of children showed AR before 57 months and the degree of obesity at the age of 57 months had a close correlation with early AR or rapid weight gain during infancy.