The association of primary aldosteronism with glaucoma-related fundus abnormalities

To elucidate glaucoma-related fundus abnormalities in patients with primary aldosteronism (PA). The study compared 272 eyes from 137 PA patients and 352 eyes from 177 control subjects selected randomly from 1173 participants of a public glaucoma screening. The presence of glaucomatous optic disc app...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2020-11, Vol.15 (11), p.e0242090-e0242090
Main Authors: Ohshima, Yoshimi, Higashide, Tomomi, Sakaguchi, Kimikazu, Sasaki, Makoto, Udagawa, Sachiko, Ohkubo, Shinji, Yoneda, Takashi, Sugiyama, Kazuhisa
Format: Article
Language:English
Subjects:
Abnormalities
Aged
Biology and Life Sciences
Blood pressure
Blood vessels
Case-Control Studies
Diabetes
Diagnostic Techniques, Ophthalmological
Endocrine disorders
Enlargement
Eye
Eye (anatomy)
Female
Fundus Oculi
Glaucoma
Glaucoma - diagnosis
Glaucoma - epidemiology
Glaucoma - pathology
Humans
Hyperaldosteronism
Hyperaldosteronism - complications
Hyperaldosteronism - pathology
Hypertension
Hypotension
Japan
Male
Mass Screening
Medical screening
Medicine and Health Sciences
Middle Aged
Optic nerve
Patients
Physiological aspects
Prevalence
Retina
Risk factors
University graduates
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To elucidate glaucoma-related fundus abnormalities in patients with primary aldosteronism (PA). The study compared 272 eyes from 137 PA patients and 352 eyes from 177 control subjects selected randomly from 1173 participants of a public glaucoma screening. The presence of glaucomatous optic disc appearance (rim thinning and cup enlargement) and retinal nerve fiber layer defects (RNFLDs) was determined independently from fundus photographs. The results were compared between the PA and control groups. There were 9 patients (6.6%) with glaucomatous optic disc abnormalities in the PA group and 10 cases (5.6%) identified in the control group (p = 0.92). RNFLDs were detected more frequently in the PA group (55 eyes, 20.2%) than in the control group (26 eyes, 7.4%; p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0242090