Novel measurement tool and model for aberrant urinary stream in 3D printed urethras derived from human tissue

An estimated 10% of male adults have split or dribbled stream leading to poor hygiene, embarrassment, and inconvenience. There is no current metric that measures male stream deviation. To develop a novel method to measure spray in normal and abnormal anatomical conformations. We developed a novel pl...

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Bibliographic Details
Published in:PloS one 2020-11, Vol.15 (11), p.e0241507
Main Authors: Cohen, Andrew J, Patino, German, Mirramezani, Mehran, Srirangapatanam, Sudarshan, Tresh, Anas, Cheema, Bhagat, Tai, Jenny, Romero, Dylan, Enriquez, Anthony, Baskin, Laurence S, Shadden, Shawn C, Breyer, Benjamin N
Format: Article
Language:English
Subjects:
Artificial organs
Biology and Life Sciences
Cadaver
Cadavers
Computer applications
Deviation
Dynamic models
Engineering and technology
Experiments
Flow (Dynamics)
Human tissues
Humans
Hydrodynamics
Hygiene
Measurement
Mechanical engineering
Medical research
Medicine and Health Sciences
Models, Biological
Obstructions
Pattern analysis
Penis
Physical Sciences
Physiological aspects
Printing, Three-Dimensional
Quality of life
Relative vorticity
Statistical analysis
Surgery
Three dimensional flow
Three dimensional models
Three dimensional printing
Tissues
Urethra
Urethra - physiology
Urination
Urination - physiology
Urine
Urology
Vorticity
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Summary:An estimated 10% of male adults have split or dribbled stream leading to poor hygiene, embarrassment, and inconvenience. There is no current metric that measures male stream deviation. To develop a novel method to measure spray in normal and abnormal anatomical conformations. We developed a novel platform to reliably describe spray. We used cadaveric tissues and 3D Printed models to study the impact of meatal shape on the urinary stream. Cadaveric penile tissue and 3D printed models were affixed to a fluid pump and used to simulate micturition. Dye captured on fabric allowed for spray detection. Spray pattern area, deviation from normal location, and flowrates were recorded. Computational fluid dynamic models were created to study fluid vorticity. Obstructions at the penile tip worsened spray dynamics and reduced flow. Ventral meatotomy improved flowrate (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0241507