Lemongrass (Cymbopogon citratus) oil: A promising miticidal and ovicidal agent against Sarcoptes scabiei

Essential oils may represent an alternative strategy for controlling scabies, a neglected tropical disease caused by the infestation of mite from the species Sarcoptes scabiei. Lemongrass (Cymbopogen citratus) oil is reported to possess pharmacological properties including antiparasitc, antioxidant,...

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Bibliographic Details
Published in:PLoS neglected tropical diseases 2020-04, Vol.14 (4), p.e0008225-e0008225
Main Authors: Li, Meilin, Liu, Buming, Bernigaud, Charlotte, Fischer, Katja, Guillot, Jacques, Fang, Fang
Format: Article
Language:English
Subjects:
Acaricides
Animal sciences
Antiinfectives and antibacterials
Antioxidants
Biology and Life Sciences
Chromatography
Citral
Control
Earth Sciences
Eggs
Essential oils
Fruits
Hatching
Health aspects
Humidity
Infestation
Inflammation
Laboratories
Lemongrass oil
Lethal limits
Mass spectrometry
Mass spectroscopy
Medicine and Health Sciences
Mites
Mortality
Oil
Oils & fats
Parasitology
Physical Sciences
Physiological aspects
Prevention
Rabbits
Research and Analysis Methods
Sarcoptes scabiei
Scabies
Scientific imaging
Tropical climate
Tropical diseases
Variance analysis
Zoology
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Summary:Essential oils may represent an alternative strategy for controlling scabies, a neglected tropical disease caused by the infestation of mite from the species Sarcoptes scabiei. Lemongrass (Cymbopogen citratus) oil is reported to possess pharmacological properties including antiparasitc, antioxidant, antimicrobial and anti-inflammatory. The aim of the present study was to assess the potential efficacy of lemongrass oil against the mites and eggs of Sarcoptes scabiei. Mass spectrometry analysis confirmed that the main component presented in lemongrass oil was citral. Lemongrass oil at concentrations of 10% and 5% killed all Sarcoptes mites within 10 and 25 min, respectively. The median lethal concentration value was 1.37%, 1.08%, 0.91%, 0.64%, and 0.48% at 1, 3, 6, 12, and 24 h, respectively. Lemongrass oil at all concentrations (10%, 5%, 1%, 0.5%, 0.1%) was able to significantly decrease the hatching rate of Sarcoptes eggs. Lemongrass oil should be considered as a promising miticidal and ovicidal agent for scabies control.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0008225