The effects of prolonged sitting, prolonged standing, and activity breaks on vascular function, and postprandial glucose and insulin responses: A randomised crossover trial

The objective of this study was to compare acute effects of prolonged sitting, prolonged standing and sitting interrupted with regular activity breaks on vascular function and postprandial glucose metabolism. In a randomized cross-over trial, 18 adults completed: 1. Prolonged Sitting; 2. Prolonged S...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2021-01, Vol.16 (1), p.e0244841
Main Authors: Peddie, Meredith C, Kessell, Chris, Bergen, Tom, Gibbons, Travis D, Campbell, Holly A, Cotter, James D, Rehrer, Nancy J, Thomas, Kate N
Format: Article
Language:English
Subjects:
Acute effects
Adaptation
Adult
Area Under Curve
Arterial Pressure - physiology
Atherosclerosis
Biology and Life Sciences
Blood
Blood flow
Blood Glucose - metabolism
Cardiovascular disease
Cross-Over Studies
Diabetes
Energy
Exercise
Exercise - physiology
Female
Glucose
Glucose - metabolism
Health aspects
Hemodynamics
Hemodynamics - physiology
Humans
Hyperglycemia - metabolism
Insulin
Insulin - metabolism
Insulin, Regular, Human - metabolism
Intervention
Male
Medicine and Health Sciences
Metabolism
Physical activity
Physical education
Physical fitness
Physical Sciences
Physiological research
Postprandial Period
Posture
Sedentary Behavior
Shear rate
Shear stress
Sitting Position
Standing Position
Triglycerides - blood
Veins & arteries
Walking - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of this study was to compare acute effects of prolonged sitting, prolonged standing and sitting interrupted with regular activity breaks on vascular function and postprandial glucose metabolism. In a randomized cross-over trial, 18 adults completed: 1. Prolonged Sitting; 2. Prolonged Standing and 3. Sitting with 2-min walking (5 km/h, 10% incline) every 30 min (Regular Activity Breaks). Flow mediated dilation (FMD) was measured in the popliteal artery at baseline and 6 h. Popliteal artery hemodynamics, and postprandial plasma glucose and insulin were measured over 6 h. Neither raw nor allometrically-scaled FMD showed an intervention effect (p = 0.285 and 0.159 respectively). Compared to Prolonged Sitting, Regular Activity Breaks increased blood flow (overall effect of intervention p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0244841