Effects of Chinese wolfberry and Astragalus extract on the antioxidant capacity of Tibetan pig liver

• Published in: PloS one 2021-01, Vol.16 (1), p.e0245749-e0245749
• Main Authors: Hao, Zhuang, Li, Zhen, Huo, Jinjin, Li, Jiandong, Liu, Fenghua, Yin, Peng
• Format: Article
• Language: English
• Subjects: Animal husbandry; Animal sciences; Animals; Antioxidants; Antioxidants - pharmacology; Astragalus (Plants); Astragalus membranaceus; Astragalus Plant - chemistry; Biology and Life Sciences; Biotechnology industry; Breeding; Breeding methods; Chemical synthesis; Coliforms; Deoxyribonucleic acid; Diet; DNA; DNA biosynthesis; DNA polymerase; DNA-directed DNA polymerase; E coli; Economic impact; Enzymes; Exonuclease; Free radicals; Gases; Gene expression; Genomes; Health aspects; High fat diet; High protein diet; High temperature; Hogs; Immune response; Ingredients; Intestine; Laboratory animals; Liver; Liver - drug effects; Liver - metabolism; Lycium; Lycium - chemistry; Lycium barbarum; Oligonucleotides; Oxidative stress; People and Places; Peroxins - genetics; Peroxins - metabolism; Peroxisomes - metabolism; Physiological aspects; Plant extracts; Plant Extracts - pharmacology; Polysaccharides; Ribonuclease H; Saccharides; Signal Transduction; Swine; Weaning; Zoology
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0245749

The objective of this study is to determine the effect of Chinese wolfberry (Lycium barbarum) and Astragalus (Astragalus membranaceus) extract (WAE) on the antioxidant capacity of Tibetan pig liver, and discussed the regulatory effect of WAE on the liver antioxidant mechanism. Twelve healthy 120-day-old Tibetan black pigs (35±2 kg) were divided randomly into two groups. The WAE group was fed a basal diet supplemented with 1% WAE for 90 days. The control group was fed the same diet, but without the WAE. We found that liver superoxide dismutase 1 (SOD1) activity (P