Sonographic findings in coronavirus disease-19 associated liver damage

This study was conducted to evaluate the role of liver sonography in patients with coronavirus disease 2019 (COVID-19) and elevated liver enzymes. In this retrospective study, patients tested positive for SARS-CoV-2 in our emergency ward between January 01 and April 24, 2020 and elevated liver enzym...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2021-02, Vol.16 (2), p.e0244781-e0244781
Main Authors: Spogis, Jakob, Hagen, Florian, Thaiss, Wolfgang M, Hoffmann, Tatjana, Malek, Nisar, Nikolaou, Konstantin, Berg, Christoph P, Singer, Stephan, Bösmüller, Hans, Kreth, Florian, Kaufmann, Sascha
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Alanine
Alanine transaminase
Anoxia
Ascites
Bile ducts
Biology and Life Sciences
Cholestasis
Coronaviridae
Coronaviruses
COVID-19
COVID-19 - complications
COVID-19 - diagnostic imaging
Cytotoxicity
Damage
Diagnosis
Diagnosis, Ultrasonic
Diagnostic systems
Editing
Emergency medical care
Emergency medical services
Enzymes
Female
Gallbladder
Hepatic artery
Hepatitis
Hospitals
Humans
Infections
Inflammation
Inflammatory response
Information systems
Intensive care
Internal medicine
Laboratories
Liver
Liver - diagnostic imaging
Liver diseases
Liver Diseases - diagnostic imaging
Liver Diseases - etiology
Male
Medical research
Medicine
Medicine and Health Sciences
Medicine, Experimental
Methodology
Middle Aged
Nuclear medicine
Pathology
Patients
Portal vein
Radiology
Research and Analysis Methods
Retrospective Studies
Risk factors
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Statistical analysis
Thickening
Toxicity
Ultrasonic imaging
Ultrasonography
Veins & arteries
Viral diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study was conducted to evaluate the role of liver sonography in patients with coronavirus disease 2019 (COVID-19) and elevated liver enzymes. In this retrospective study, patients tested positive for SARS-CoV-2 in our emergency ward between January 01 and April 24, 2020 and elevated liver enzymes were included (Cohort 1). Additionally, the local radiology information system was screened for sonographies in COVID-19 patients at the intensive care unit in the same period (Cohort 2). Liver sonographies and histologic specimen were reviewed and suspicious findings recorded. Medical records were reviewed for clinical data. Ultrasound findings and clinical data were correlated with severity of liver enzyme elevation. Cohort 1: 126 patients were evaluated, of which 47 (37.3%) had elevated liver enzymes. Severity of liver enzyme elevation was associated with death (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0244781