Hourly fetal urine production rate in isolated oligohydramnios at term

• Published in: PloS one 2021-05, Vol.16 (5), p.e0250659
• Main Authors: Seol, Hyun-Joo, Kim, Ho Yeon, Cho, Geum-Joon, Oh, Min-Jeong
• Format: Article
• Language: English
• Subjects: Absorption; Adult; Amniotic Fluid; Biology and Life Sciences; Bladder; Complications and side effects; Female; Fetal Growth Retardation - diagnostic imaging; Fetus - diagnostic imaging; Fetuses; Gestational Age; Gynecology; Humans; Hypoxia; Medical schools; Medicine; Medicine and Health Sciences; Mortality; Obstetrics; Oligohydramnios; Oligohydramnios - diagnostic imaging; Pregnancy; Prospective Studies; Research and Analysis Methods; Ultrasonic imaging; Ultrasonography, Prenatal; Urine; Womens health
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0250659

The aim of this study was to evaluate the hourly fetal urine production rate (HFUPR) via three-dimensional ultrasonography in women with isolated oligohydramnios and compare with normal pregnant women at term. This was a prospective observational cohort study of 112 women from 34 to 40 6/7 weeks' gestation. They were classified into three groups according to the amniotic fluid index (AFI) and ultrasonographic estimated fetal weight (EFW) as isolated oligohydramnios (defined as AFI below 5% and appropriate EFW corresponding to gestational age) (n = 34) and IUGR (defined as EFW below 5% corresponding to gestational age irrespective amniotic fluid) (n = 17), and normal pregnancy (n = 61). HFUPR was measured using three-dimensional virtual organ computer-aided analysis. Adverse perinatal outcomes in all participants were examined. There was no significant difference in HFUPR between patients with isolated oligohydramnios and women with normal pregnancies (median, 40.0 mL/h [interquartile range [IQR] 31.0-66.5] vs. 48.6 [31.5-81.2], p = 0.224). HFUPR was significantly decreased in the IUGR group (13.8 mL/h [IQR 10.1-24.8]), compared to the normal pregnancy group (p