Update: Gender differences in CABG outcomes—Have we bridged the gap?

Appreciation of unique presentation, patterns and underlying pathophysiology of coronary artery disease in women has driven gender based risk stratification and risk reduction efforts over the last decade. Data regarding whether these advances have resulted in unequivocal improvements in outcomes of...

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Bibliographic Details
Published in:PloS one 2021-09, Vol.16 (9), p.e0255170-e0255170
Main Authors: Matyal, Robina, Qureshi, Nada Qaisar, Mufarrih, Syed Hamza, Sharkey, Aidan, Bose, Ruma, Chu, Louis M, Liu, David C, Senthilnathan, Venkatachalam, Mahmood, Feroze, Khabbaz, Kamal R
Format: Article
Language:English
Subjects:
Biology and Life Sciences
Body mass index
Cardiovascular disease
Cardiovascular diseases
Care and treatment
Coronary artery
Coronary artery bypass
Coronary artery disease
Coronary vessels
Critical care
Demographic aspects
Diabetes
Diabetes mellitus
Ejection fraction
Engineering and Technology
Epidemiology
Females
Gender
Gender aspects
Gender differences
Heart attacks
Heart diseases
Heart failure
Heart surgery
Males
Medical schools
Medicine
Medicine and Health Sciences
Men
Morbidity
Mortality
Pain
Patient outcomes
Patients
Postoperative period
Regression analysis
Risk management
Sex differences
Thorax
Variables
Ventilators
Women
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Summary:Appreciation of unique presentation, patterns and underlying pathophysiology of coronary artery disease in women has driven gender based risk stratification and risk reduction efforts over the last decade. Data regarding whether these advances have resulted in unequivocal improvements in outcomes of CABG in women is conflicting. The objective of our study was to assess gender differences in post-operative outcomes following CABG. Retrospective analyses of institutional data housed in the Society of Thoracic Surgeons (STS) database for patients undergoing CABG between 2002 and 2020 were conducted. Multivariable regression analysis was conducted to investigate gender differences in post-operative outcomes. P-values were adjusted using Bonferroni correction to reduce type-I errors. Our final cohort of 6,250 patients had fewer women than men (1,339 vs. 4,911). more women were diabetic (52.0% vs. 41.2%, p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0255170