The potential impact of triage protocols on racial disparities in clinical outcomes among COVID-positive patients in a large academic healthcare system

• Published in: PloS one 2021-09, Vol.16 (9), p.e0256763-e0256763
• Main Authors: Roy, Shireen, Showstark, Mary, Tolchin, Benjamin, Kashyap, Nitu, Bonito, Jennifer, Salazar, Michelle C, Herbst, Jennifer L, Nash, Katherine A, Nguemeni Tiako, Max Jordan, Jubanyik, Karen, Kim, Nancy, Galusha, Deron, Wang, Karen H, Oladele, Carol
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Biology and Life Sciences; Black or African American - statistics & numerical data; Clinical outcomes; Computer and Information Sciences; Connecticut; Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 - prevention & control; COVID-19 - virology; Delivery of Health Care - statistics & numerical data; Demographic aspects; Emergency medical care; Engineering and Technology; Female; Health aspects; Health care; Health care disparities; Healthcare Disparities - ethnology; Healthcare Disparities - statistics & numerical data; Hispanic or Latino - statistics & numerical data; Hospital Mortality - ethnology; Hospitals, University; Humans; Male; Medicine and Health Sciences; Middle Aged; Minority & ethnic groups; Mortality; Organ Dysfunction Scores; Pandemics; Patients; People and Places; Race factors; Races; Racism; Retrospective Studies; SARS-CoV-2 - physiology; Social Sciences; Triage - methods; Triage - statistics & numerical data; Variance analysis; White People - statistics & numerical data; Young Adult
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0256763

The COVID-19 pandemic has had a devastating impact in the United States, particularly for Black populations, and has heavily burdened the healthcare system. Hospitals have created protocols to allocate limited resources, but there is concern that these protocols will exacerbate disparities. The sequential organ failure assessment (SOFA) score is a tool often used in triage protocols. In these protocols, patients with higher SOFA scores are denied resources based on the assumption that they have worse clinical outcomes. The purpose of this study was to assess whether using SOFA score as a triage tool among COVID-positive patients would exacerbate racial disparities in clinical outcomes. We analyzed data from a retrospective cohort of hospitalized COVID-positive patients in the Yale-New Haven Health System. We examined associations between race/ethnicity and peak overall/24-hour SOFA score, in-hospital mortality, and ICU admission. Other predictors of interest were age, sex, primary language, and insurance status. We used one-way ANOVA and chi-square tests to assess differences in SOFA score across racial/ethnic groups and linear and logistic regression to assess differences in clinical outcomes by sociodemographic characteristics. Our final sample included 2,554 patients. Black patients had higher SOFA scores compared to patients of other races. However, Black patients did not have significantly greater in-hospital mortality or ICU admission compared to patients of other races. While Black patients in this sample of hospitalized COVID-positive patients had higher SOFA scores compared to patients of other races, this did not translate to higher in-hospital mortality or ICU admission. Results demonstrate that if SOFA score had been used to allocate care, Black COVID patients would have been denied care despite having similar clinical outcomes to white patients. Therefore, using SOFA score to allocate resources has the potential to exacerbate racial inequities by disproportionately denying care to Black patients and should not be used to determine access to care. Healthcare systems must develop and use COVID-19 triage protocols that prioritize equity.