Loading…

A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies

In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of (pre)registered protocols is still low, illustrating the need for pushing the preregistration agenda among researchers and policymakers.

Saved in:
Bibliographic Details
Published in:PLoS biology 2021-09, Vol.19 (9), p.e3001397-e3001397
Main Authors: van der Naald, Mira, Chamuleau, Steven A. J, Menon, Julia M. L, de Leeuw, Wim, de Haan, Judith J, Duncker, Dirk J, Wever, Kimberley E
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333
cites cdi_FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333
container_end_page e3001397
container_issue 9
container_start_page e3001397
container_title PLoS biology
container_volume 19
creator van der Naald, Mira
Chamuleau, Steven A. J
Menon, Julia M. L
de Leeuw, Wim
de Haan, Judith J
Duncker, Dirk J
Wever, Kimberley E
description In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of (pre)registered protocols is still low, illustrating the need for pushing the preregistration agenda among researchers and policymakers.
doi_str_mv 10.1371/journal.pbio.3001397
format article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2582586658</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A677985583</galeid><doaj_id>oai_doaj_org_article_7b4fe5d10b654104899ac79fb5e86b92</doaj_id><sourcerecordid>A677985583</sourcerecordid><originalsourceid>FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333</originalsourceid><addsrcrecordid>eNqVk9-L1DAQx4so3nn6HwgWfNGHXdMmaZMXYTn8sXB44K_XMEkna5a0WZN28f57s249XLkHJYEMk898ZzJhiuJpRZYVbatX2zDFAfxyp11YUkIqKtt7xXnFGV-0QvD7f9hnxaOUtoTUtazFw-KMMiZlw8h50a9KurhBiCXuwU8wujCUwZa7iMa7wRnwY3Tg0xKnMuIes1nGEPrShli6fhfDHnscxtINh6CIG5fGeKsDg-vBl2mcOofpcfHAZgF8Mp8XxZe3bz5fvl9cXb9bX66uFqZp63HBDBHItYBKWhRMc00BrOxEl52cgiUSGg6WMd3pBglhloEmjeyA6o5SelE8O-rufEhq7lRSNRd5Nw0XmVgfiS7AVu1irjLeqABO_XKEuFEQR2c8qlYzi7yriG44qwgTUoJppdUcRaNlnbVez9km3WNncjci-BPR05vBfVObsFeCcSZplQVezAIxfJ8wjap3yaD3MGCYDnW3lcxf3JKMPv8Lvft1M7WB_AA32JDzmoOoWjVtKwXPUKaWd1B5ddg7Ewa0LvtPAl6eBGRmxB_jBqaU1PrTx_9gP_w7e_31lGVH1sSQUkR72-eKqMNg_G6IOgyGmgeD_gQ3dgDu</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2582586658</pqid></control><display><type>article</type><title>A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies</title><source>PubMed Central(OA)</source><source>Publicly Available Content Database</source><creator>van der Naald, Mira ; Chamuleau, Steven A. J ; Menon, Julia M. L ; de Leeuw, Wim ; de Haan, Judith J ; Duncker, Dirk J ; Wever, Kimberley E</creator><creatorcontrib>van der Naald, Mira ; Chamuleau, Steven A. J ; Menon, Julia M. L ; de Leeuw, Wim ; de Haan, Judith J ; Duncker, Dirk J ; Wever, Kimberley E</creatorcontrib><description>In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of (pre)registered protocols is still low, illustrating the need for pushing the preregistration agenda among researchers and policymakers.</description><identifier>ISSN: 1545-7885</identifier><identifier>ISSN: 1544-9173</identifier><identifier>EISSN: 1545-7885</identifier><identifier>DOI: 10.1371/journal.pbio.3001397</identifier><identifier>PMID: 34499640</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Accountability ; Bias ; Biology and Life Sciences ; Clinical trials ; Funding ; Hypotheses ; Intellectual property ; Laboratory animals ; Medical research ; Medicine and Health Sciences ; Methods ; R&amp;D ; Registration ; Research &amp; development ; Research and Analysis Methods ; Researchers ; Science Policy ; Social Sciences ; Transparency</subject><ispartof>PLoS biology, 2021-09, Vol.19 (9), p.e3001397-e3001397</ispartof><rights>COPYRIGHT 2021 Public Library of Science</rights><rights>2021 van der Naald et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 van der Naald et al 2021 van der Naald et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333</citedby><cites>FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333</cites><orcidid>0000-0003-2836-2241 ; 0000-0002-4949-625X ; 0000-0002-9952-6701 ; 0000-0003-3635-3660 ; 0000-0001-6745-4646 ; 0000-0002-3467-1908</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2582586658/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2582586658?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids></links><search><creatorcontrib>van der Naald, Mira</creatorcontrib><creatorcontrib>Chamuleau, Steven A. J</creatorcontrib><creatorcontrib>Menon, Julia M. L</creatorcontrib><creatorcontrib>de Leeuw, Wim</creatorcontrib><creatorcontrib>de Haan, Judith J</creatorcontrib><creatorcontrib>Duncker, Dirk J</creatorcontrib><creatorcontrib>Wever, Kimberley E</creatorcontrib><title>A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies</title><title>PLoS biology</title><description>In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of (pre)registered protocols is still low, illustrating the need for pushing the preregistration agenda among researchers and policymakers.</description><subject>Accountability</subject><subject>Bias</subject><subject>Biology and Life Sciences</subject><subject>Clinical trials</subject><subject>Funding</subject><subject>Hypotheses</subject><subject>Intellectual property</subject><subject>Laboratory animals</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Methods</subject><subject>R&amp;D</subject><subject>Registration</subject><subject>Research &amp; development</subject><subject>Research and Analysis Methods</subject><subject>Researchers</subject><subject>Science Policy</subject><subject>Social Sciences</subject><subject>Transparency</subject><issn>1545-7885</issn><issn>1544-9173</issn><issn>1545-7885</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqVk9-L1DAQx4so3nn6HwgWfNGHXdMmaZMXYTn8sXB44K_XMEkna5a0WZN28f57s249XLkHJYEMk898ZzJhiuJpRZYVbatX2zDFAfxyp11YUkIqKtt7xXnFGV-0QvD7f9hnxaOUtoTUtazFw-KMMiZlw8h50a9KurhBiCXuwU8wujCUwZa7iMa7wRnwY3Tg0xKnMuIes1nGEPrShli6fhfDHnscxtINh6CIG5fGeKsDg-vBl2mcOofpcfHAZgF8Mp8XxZe3bz5fvl9cXb9bX66uFqZp63HBDBHItYBKWhRMc00BrOxEl52cgiUSGg6WMd3pBglhloEmjeyA6o5SelE8O-rufEhq7lRSNRd5Nw0XmVgfiS7AVu1irjLeqABO_XKEuFEQR2c8qlYzi7yriG44qwgTUoJppdUcRaNlnbVez9km3WNncjci-BPR05vBfVObsFeCcSZplQVezAIxfJ8wjap3yaD3MGCYDnW3lcxf3JKMPv8Lvft1M7WB_AA32JDzmoOoWjVtKwXPUKaWd1B5ddg7Ewa0LvtPAl6eBGRmxB_jBqaU1PrTx_9gP_w7e_31lGVH1sSQUkR72-eKqMNg_G6IOgyGmgeD_gQ3dgDu</recordid><startdate>20210909</startdate><enddate>20210909</enddate><creator>van der Naald, Mira</creator><creator>Chamuleau, Steven A. J</creator><creator>Menon, Julia M. L</creator><creator>de Leeuw, Wim</creator><creator>de Haan, Judith J</creator><creator>Duncker, Dirk J</creator><creator>Wever, Kimberley E</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISN</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PATMY</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><scope>CZG</scope><orcidid>https://orcid.org/0000-0003-2836-2241</orcidid><orcidid>https://orcid.org/0000-0002-4949-625X</orcidid><orcidid>https://orcid.org/0000-0002-9952-6701</orcidid><orcidid>https://orcid.org/0000-0003-3635-3660</orcidid><orcidid>https://orcid.org/0000-0001-6745-4646</orcidid><orcidid>https://orcid.org/0000-0002-3467-1908</orcidid></search><sort><creationdate>20210909</creationdate><title>A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies</title><author>van der Naald, Mira ; Chamuleau, Steven A. J ; Menon, Julia M. L ; de Leeuw, Wim ; de Haan, Judith J ; Duncker, Dirk J ; Wever, Kimberley E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Accountability</topic><topic>Bias</topic><topic>Biology and Life Sciences</topic><topic>Clinical trials</topic><topic>Funding</topic><topic>Hypotheses</topic><topic>Intellectual property</topic><topic>Laboratory animals</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Methods</topic><topic>R&amp;D</topic><topic>Registration</topic><topic>Research &amp; development</topic><topic>Research and Analysis Methods</topic><topic>Researchers</topic><topic>Science Policy</topic><topic>Social Sciences</topic><topic>Transparency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van der Naald, Mira</creatorcontrib><creatorcontrib>Chamuleau, Steven A. J</creatorcontrib><creatorcontrib>Menon, Julia M. L</creatorcontrib><creatorcontrib>de Leeuw, Wim</creatorcontrib><creatorcontrib>de Haan, Judith J</creatorcontrib><creatorcontrib>Duncker, Dirk J</creatorcontrib><creatorcontrib>Wever, Kimberley E</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Canada</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><collection>PLoS Biology</collection><jtitle>PLoS biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van der Naald, Mira</au><au>Chamuleau, Steven A. J</au><au>Menon, Julia M. L</au><au>de Leeuw, Wim</au><au>de Haan, Judith J</au><au>Duncker, Dirk J</au><au>Wever, Kimberley E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies</atitle><jtitle>PLoS biology</jtitle><date>2021-09-09</date><risdate>2021</risdate><volume>19</volume><issue>9</issue><spage>e3001397</spage><epage>e3001397</epage><pages>e3001397-e3001397</pages><issn>1545-7885</issn><issn>1544-9173</issn><eissn>1545-7885</eissn><abstract>In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of (pre)registered protocols is still low, illustrating the need for pushing the preregistration agenda among researchers and policymakers.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>34499640</pmid><doi>10.1371/journal.pbio.3001397</doi><orcidid>https://orcid.org/0000-0003-2836-2241</orcidid><orcidid>https://orcid.org/0000-0002-4949-625X</orcidid><orcidid>https://orcid.org/0000-0002-9952-6701</orcidid><orcidid>https://orcid.org/0000-0003-3635-3660</orcidid><orcidid>https://orcid.org/0000-0001-6745-4646</orcidid><orcidid>https://orcid.org/0000-0002-3467-1908</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1545-7885
ispartof PLoS biology, 2021-09, Vol.19 (9), p.e3001397-e3001397
issn 1545-7885
1544-9173
1545-7885
language eng
recordid cdi_plos_journals_2582586658
source PubMed Central(OA); Publicly Available Content Database
subjects Accountability
Bias
Biology and Life Sciences
Clinical trials
Funding
Hypotheses
Intellectual property
Laboratory animals
Medical research
Medicine and Health Sciences
Methods
R&D
Registration
Research & development
Research and Analysis Methods
Researchers
Science Policy
Social Sciences
Transparency
title A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T15%3A52%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%203-year%20evaluation%20of%20preclinicaltrials.eu%20reveals%20room%20for%20improvement%20in%20preregistration%20of%20animal%20studies&rft.jtitle=PLoS%20biology&rft.au=van%20der%20Naald,%20Mira&rft.date=2021-09-09&rft.volume=19&rft.issue=9&rft.spage=e3001397&rft.epage=e3001397&rft.pages=e3001397-e3001397&rft.issn=1545-7885&rft.eissn=1545-7885&rft_id=info:doi/10.1371/journal.pbio.3001397&rft_dat=%3Cgale_plos_%3EA677985583%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c672t-4c08e5b8a19fe84b5b3aaf9d8d5b853af09a65af44bdb6e004f4ab069da3bd333%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2582586658&rft_id=info:pmid/34499640&rft_galeid=A677985583&rfr_iscdi=true