Predicting singleton antepartum stillbirth by the demographic Fetal Medicine Foundation Risk Calculator-A retrospective case-control study

To assess the risk of singleton intrauterine fetal death (IUFD) in women by the demographic setting of the online Fetal Medicine Foundation (FMF) Stillbirth Risk Calculator. Retrospective single-centre case-control study involving 144 women having suffered IUFD and 247 women after delivery of a live...

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Bibliographic Details
Published in:PloS one 2022-01, Vol.17 (1), p.e0260964
Main Authors: Muin, Dana A, Windsperger, Karin, Attia, Nadia, Kiss, Herbert
Format: Article
Language:English
Subjects:
Adult
Age
Antiphospholipid syndrome
Births
Case-Control Studies
Congenital defects
Demographic aspects
Demographics
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Ethnicity
Female
Fetal Death
Fetuses
Gynecology
Health risks
Humans
Hypertension
Insulin
Mathematical analysis
Medicine
Medicine and Health Sciences
Obesity
Obstetrics
Pediatrics
Placental abruption
Preeclampsia
Pregnancy
Retrospective Studies
Risk Assessment - methods
Risk Factors
ROC Curve
Still-birth
Stillbirth
Stillbirth - epidemiology
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Summary:To assess the risk of singleton intrauterine fetal death (IUFD) in women by the demographic setting of the online Fetal Medicine Foundation (FMF) Stillbirth Risk Calculator. Retrospective single-centre case-control study involving 144 women having suffered IUFD and 247 women after delivery of a live-born singleton. Nonparametric receiver operating characteristics (ROC) analyses were performed to predict the prognostic power of the FMF Stillbirth risk score and to generate a cut-off value to discriminate best between the event of IUFD versus live birth. Women in the IUFD cohort born a significantly higher overall risk with a median FMF risk score of 0.45% (IQR 0.23-0.99) compared to controls [0.23% (IQR 0.21-0.29); p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0260964