Percentage of body fat is associated with increased risk of diverticulosis: A cross sectional study

• Published in: PloS one 2022-03, Vol.17 (3), p.e0264746-e0264746
• Main Authors: Shih, Chi-Wei, Chen, Yu-Hsin, Chen, Wei-Liang
• Format: Article
• Language: English
• Subjects: Abdomen; Adipose tissues; Age; Alcohol; Alcohol use; Auroral kilometric radiation; Bioelectricity; Biology and Life Sciences; Body composition; Body fat; Cholesterol; Colon; Colonoscopy; Creatinine; Cross-sectional studies; Diverticulitis; Diverticulosis; Emergency medical care; Fasting; Females; Gender; Glucose; Health aspects; Health care facilities; Health risks; Hospitals; Males; Measurement; Medicine; Medicine and Health Sciences; Methods; Obesity; Physical Sciences; Prevention; Questionnaires; Radiation; Risk analysis; Risk factors; Sex differences; Subgroups; Tomography; Triglycerides
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0264746

Obesity has been indicated to be a risk factor of diverticulosis. However, plausible relationship remained controversial. This cross-sectional study elucidated the association between percentage of body fat and the risk of diverticulosis. The study was conducted at a single medical center in Taiwan from 2000-2016 which enrolled 5557 adults with age above 20 years old receiving a health examination including self-reported questionnaires, measurement of percentage of body fat (PBF), blood test and colonoscopy at the Tri-Service General Hospital (TSGH). Logistic regressions were used to analyze the association between PBF and diverticulosis. Further stratification of participants was based on age and gender and three extended models were established for multivariable adjustment. 243 of 3141 males and 103 of 2416 females were diagnosed with having diverticulosis. After covariates adjustment, only participants in the highest quartile of PBF (Q4 ≥33.8%) showed significantly positive association with the risk diverticulosis (OR 2.089, p