Low cost multifunctional 3D printed image quality and dose verification phantom for an image-guided radiotherapy system

• Published in: PloS one 2022-04, Vol.17 (4), p.e0266604-e0266604
• Main Authors: Wu, Jian-Kuen, Yu, Min-Chin, Chen, Shih-Han, Liao, Shu-Hsien, Wang, Yu-Jen
• Format: Article
• Language: English
• Subjects: 3-D printers; Auroral kilometric radiation; Biology and Life Sciences; Calibration; Computed tomography; CT imaging; Drug dosages; Engineering and technology; Evaluation; Humans; Image Processing, Computer-Assisted - methods; Image quality; International standardization; International standards; Linear accelerators; Low cost; Magnetic resonance; Magnetic resonance imaging; Medical imaging; Medicine and Health Sciences; Modules; Oncology; Particle Accelerators; Phantoms, Imaging; Physical Sciences; Printing, Three-Dimensional; Quality assurance; Quality control; Radiation; Radiation damage; Radiation therapy; Radiology; Radiotherapy; Radiotherapy, Image-Guided - methods; Research and Analysis Methods; Simulation; Simulators; Slabs; Spatial discrimination; Spatial resolution; Three dimensional printing; Tomography; Tumors
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0266604

Image-guided radiation therapy (IGRT) is used to precisely deliver radiation to a tumour to reduce the possible damage to the surrounding normal tissues. Clinics use various quality assurance (QA) equipment to ensure that the performance of the IGRT system meets the international standards set for the system. The objective of this study was to develop a low-cost and multipurpose module for evaluating image quality and dose. A multipurpose phantom was designed to meet the clinical requirements of high accuracy, easy setup, and calibration. The outer shell of the phantom was fabricated using acrylic. Three dimensional (3D) printing technology was used to fabricate inner slabs with the characteristics of high spatial resolution, low-contrast detectability, a 3D grid, and liquid-filled uniformity. All materials were compatible with magnetic resonance (MR). Computed tomography (CT) simulator and linear accelerator (LINAC) modules were developed and validated. The uniformity slab filled with water is ideal for the assessment of Hounsfield units, whereas that filled with wax is suitable for consistency checks. The high-spatial-resolution slab enables measurements with a resolution up to 5 lp/cm. The low-contrast detectability slab contains rods of 5 different sizes that can be clearly visualised. These components meet the American College of Radiology (ACR) standards for QA of CT simulators and LINACs. The multifunctional phantom module meets the ACR recommended QA guidelines and is suitable for both LINACs and CT-sim. Further measurements in an MR simulator and an MR linear accelerator (MR-LINAC) will be arranged in the future.