Are lipid ratios and triglyceride-glucose index associated with critical care outcomes in COVID-19 patients?

Lipid ratios and the triglyceride and glucose index (TyG) could be a simple biochemical marker of insulin resistance (IR). The current study was carried out to examine the correlation between triglyceride to high-density lipoprotein-cholesterol (TG/HDL-C), total cholesterol to HDL-C (TC/HDL-C), low-...

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Bibliographic Details
Published in:PloS one 2022-08, Vol.17 (8), p.e0272000-e0272000
Main Authors: Rohani-Rasaf, Marzieh, Mirjalili, Kosar, Vatannejad, Akram, Teimouri, Maryam
Format: Article
Language:English
Subjects:
Biochemical markers
Biology and Life Sciences
Body mass index
Cholesterol
Coronaviruses
Correlation
COVID-19
COVID-19 vaccines
Critical care
Density
Epidemics
Glucose
Health aspects
High density lipoprotein
Insulin
Insulin resistance
Laboratories
Lipids
Low density lipoprotein
Markers
Medical prognosis
Medicine and Health Sciences
Metabolic syndrome
Mortality
Pandemics
People and Places
Regression analysis
Regression models
Risk factors
Severe acute respiratory syndrome coronavirus 2
Statistical analysis
Triglycerides
Ventilators
Viral diseases
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Summary:Lipid ratios and the triglyceride and glucose index (TyG) could be a simple biochemical marker of insulin resistance (IR). The current study was carried out to examine the correlation between triglyceride to high-density lipoprotein-cholesterol (TG/HDL-C), total cholesterol to HDL-C (TC/HDL-C), low-density lipoprotein-cholesterol to HDL-C ratio (LDL-C/HDL-C), as well as TyG index with the severity and mortality of severe coronavirus disease 2019 (COVID-19). A total of 1228 confirmed COVID-19 patients were included in the current research. Regression models were performed to evaluate the correlation between the lipid index and severity and mortality of COVID-19. The TyG index and TG/HDL-C levels were significantly higher in the severe patients (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0272000