Ocular findings, surgery details and outcomes in proliferative diabetic retinopathy patients with chronic kidney disease

We investigated the influence of impaired renal function on fundus characteristics, pars-plana vitrectomy (PPV) details, and outcomes in patients with proliferative diabetic retinopathy (PDR). A retrospective cohort study We investigated a consecutive series of PDR patients who underwent PPV. The di...

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Bibliographic Details
Published in:PloS one 2022-10, Vol.17 (10), p.e0273133-e0273133
Main Authors: Li, Jipeng, Chandra, Aman, Liu, Lin, Zhang, Lin, Xu, Jun, Zhao, Meng
Format: Article
Language:English
Subjects:
Acuity
Adhesion
Anticoagulants
Aspirin
Biology and Life Sciences
Blood
Cardiovascular disease
Care and treatment
Cataracts
Chronic kidney failure
Complications
Diabetes
Diabetes mellitus
Diabetic retinopathy
Glaucoma
Hemodialysis
Hemorrhage
Hypertension
Ischemia
Kidney diseases
Kidneys
Laboratories
Lasers
Medicine and Health Sciences
Patient outcomes
Patients
Renal function
Retina
Retinal detachment
Retinopathy
Statistical analysis
Surgery
Tomography
Visual acuity
Vitrectomy
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Summary:We investigated the influence of impaired renal function on fundus characteristics, pars-plana vitrectomy (PPV) details, and outcomes in patients with proliferative diabetic retinopathy (PDR). A retrospective cohort study We investigated a consecutive series of PDR patients who underwent PPV. The diabetic complications, previous photocoagulation, intravitreal injections before PPV, ocular findings during PPV, surgical details, short-term visual outcome and post-PPV complications were recorded and compared between patients with and without impaired renal function. 149 patients had normal renal function (67.7%), and 71 (32.3%) patients had impaired renal function; 85.4% of patients were identified with chronic kidney disease (CKD) during the preoperative assessment. Impaired renal function was related to hypertension (3.40[1.58-7.29], p = 0.002), incomplete pan-retinal photocoagulation (PRP) (3.18[1.50-6.72], p = 0.002), severe fibrovascular membrane (8.19[3.43-19.54], p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0273133