Contrast of oropharyngeal leak pressure and clinical performance of I-gel™ and LMA ProSeal™ in patients: A meta-analysis

• Published in: PloS one 2022-12, Vol.17 (12), p.e0278871
• Main Authors: Tan, Yuan, Jiang, Jingyao, Wang, Rurong
• Format: Article
• Language: English
• Subjects: Adult; Airway management; Anesthesia; Anesthesia, General - adverse effects; Anesthetics; Bias; Biology and Life Sciences; Blood; Child; Clinical trials; Complications; Confidence intervals; Cough; Dosage and administration; Equipment and supplies; General anesthesia; Humans; Insertion; Intubation; Laparoscopy; Laryngeal Masks - adverse effects; Medicine and Health Sciences; Meta-analysis; Pain; Patient outcomes; Pediatric anesthesia; Pediatrics; Pharyngitis; Pharyngitis - epidemiology; Pharyngitis - etiology; Physical Sciences; Research and Analysis Methods; Respiratory therapy; Respiratory tract; Sensitivity analysis; Success; Trachea; Ventilation
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0278871

Conflicting outcomes have been reported for the i-gel™ and laryngeal mask airway (LMA) ProSeal™ in children and adults during general anesthesia. Randomized controlled trials (RCTs) that yielded wide contrast outcomes between i-gel™ and LMA ProSeal™ were included in this meta-analysis. Two authors independently identified RCTs that compared i-gel™ with LMA ProSeal™ among patients receiving general anesthesia by performing searches in EMBASE, Cochrane, PubMed, and ScienceDirect. Discussion was adopted to resolve disagreements. Data were counted with Review Manger 5.3 and pooled by applying weighted mean difference (MD) and rlsk ratio (RR), and related 95% confidence intervals. A total of 33 RCTs with 2605 patients were included in the meta-analysis. I-gel™ provided a considerably lower oropharyngeal leak pressure [weighted average diversity (MD) = -1.53 (-2.89, -0.17), P = 0.03], incidence of blood staining on the supraglottic airway devices [RR = 0.44, (0.28, 0.69), P = 0.0003], sore throat [RR = 0.31 (0.18, 0.52), P