The relationship between glycated hemoglobin level and the stage of periodontitis in individuals without diabetes

• Published in: PloS one 2023-01, Vol.18 (1), p.e0279755
• Main Authors: Banjar, Arwa, Alyafi, Rusha, AlGhamdi, Ali, Assaggaf, Mohammad, Almarghlani, Ammar, Hassan, Shaymaa, Mealey, Brian
• Format: Article
• Language: English
• Subjects: Adult; Biology and life sciences; Blood Glucose; Classification; Demographic aspects; Dentistry; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - complications; Diabetes therapy; Diagnosis; Disease; Female; Gestational diabetes; Glycated Hemoglobin; Glycosylated hemoglobin; Gum disease; Health aspects; Hemoglobin; Humans; Hyperglycemia; Infections; Insulin; Male; Measurement; Medical diagnosis; Medical research; Medicine and Health Sciences; Medicine, Experimental; Metabolism; Pathophysiology; Periodontal disease; Periodontal diseases; Periodontitis; Periodontitis - complications; Prediabetic state; Prediabetic State - complications; Risk factors; Sample size; Statistical power; Teeth
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0279755

Glycemic control appears to have a significant impact on the relationship between periodontitis and diabetes. The current study aimed to investigate the association between the stage of periodontitis and hemoglobin A1c (HbA1c) levels in patients considered to be normoglycemic. A total of 135 patients (100 females and 35 males) with no history of diabetes were included in the study. The mean age of the participants was 38.4 years old. All patients underwent a full-mouth periodontal examination. Periodontal diagnosis was determined according to the 2017 World Workshop on the Classification of Periodontal Disease. The glycemic state of the patients was assessed using a chair-side HbA1c analyzer. Ninety patients were diagnosed with periodontitis. Higher average HbA1c levels were associated with the different stages of periodontitis (p