Saussurea costus extract as bio mediator in synthesis iron oxide nanoparticles (IONPs) and their antimicrobial ability

Saussurea costus is from medicinal plants and have therapeutic properties that were recorded in a variety of medical functions. The usage of biomaterials in the synthesis of nanoparticles is an essential strategy in green nanotechnology. Iron oxide nanoparticles (IONPs) were composed in the stage of...

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Bibliographic Details
Published in:PloS one 2023-03, Vol.18 (3), p.e0282443-e0282443
Main Author: Al-Brahim, Jehan S
Format: Article
Language:English
Subjects:
Anti-Infective Agents - pharmacology
Antiinfectives and antibacterials
Antimicrobial agents
Bacteria
Biology and Life Sciences
Biomaterials
Biomedical materials
Complications and side effects
E coli
Engineering and Technology
Evaluation
Ferric chloride
Ferric Compounds - pharmacology
Ferric oxide
Fungi
Gram-positive bacteria
Health aspects
Herbal medicine
Iron chlorides
Iron compounds
Iron oxides
Magnetic Iron Oxide Nanoparticles
Medicinal plants
Medicine and Health Sciences
Medicine, Botanic
Medicine, Herbal
Metal Nanoparticles
Morphology
Nanoparticles
Nanotechnology
Patient outcomes
Physical Sciences
Plant Extracts - pharmacology
Pneumonia
Pseudomonas aeruginosa
Research and Analysis Methods
Saussurea
Saussurea costus
Scanning electron microscopy
Synthesis
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Summary:Saussurea costus is from medicinal plants and have therapeutic properties that were recorded in a variety of medical functions. The usage of biomaterials in the synthesis of nanoparticles is an essential strategy in green nanotechnology. Iron oxide nanoparticles (IONPs) were composed in the stage of (2:1, FeCl2: FeCl3) solution by using the aqueous extract of Saussurea costus peel in an eco-friendly method to evaluate their antimicrobial property. The properties of the obtained IONPs were evaluated using a scanning (SEM) and transmission (TEM) electron microscope. The mean size of IONPs discovered by Zetasizer varies between 100 and 300 nm, with a mean particle size of 295 nm. The morphology of IONPs (γ-Fe2O3) was determined to be nearly spherical and prismatic-curved. Moreover, the antimicrobial property of IONPs was assessed with nine pathogenic microbes, revealing that the nanoparticles have antimicrobial activities with Pseudomonas aeruginosa, Escherichia coli, Shigella sp., Staphylococcus sp. and Aspergillus niger, with possible applications in the therapeutic and biomedical fields.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0282443