Sporotrichosis in the nasal mucosa: A single-center retrospective study of 37 cases from 1998 to 2020

Sporotrichosis is a subcutaneous or implantation mycosis caused by some species of the genus Sporothrix. Rio de Janeiro state, Brazil, experiences hyperendemic levels of zoonotic sporotrichosis, with increasing cases of disseminated disease, especially in people living with HIV (PLHIV). Involvement...

Full description

Saved in:
Bibliographic Details
Published in:PLoS neglected tropical diseases 2023-03, Vol.17 (3), p.e0011212
Main Authors: Izoton, Carlos Felipe Gomes, de Brito Sousa, Antonio Xavier, Valete, Cláudia Maria, Schubach, Armando de Oliveira, Procópio-Azevedo, Anna Carolina, Zancopé-Oliveira, Rosely Maria, de Macedo, Priscila Marques, Gutierrez-Galhardo, Maria Clara, Castro-Alves, Julio, Almeida-Paes, Rodrigo, Martins, Ana Cristina da Costa, Freitas, Dayvison Francis Saraiva
Format: Article
Language:English
Subjects:
Adult
Amphotericin B
Antifungal Agents - therapeutic use
Biology and Life Sciences
Biopsy
Brazil - epidemiology
Care and treatment
Classification
Comorbidity
Concretions
Crusts
Diagnosis
Drug dosages
Endoscopy
Epidemiology
Female
Health services
HIV
Human immunodeficiency virus
Humans
Immune system
Immunosuppression
Infections
Infectious diseases
Itraconazole
Itraconazole - therapeutic use
Laboratories
Lesions
Male
Medical records
Medicine and Health Sciences
Mucosa
Mycosis
Nasal Mucosa
Outpatient care facilities
Patients
Probability theory
Retrospective Studies
Sporothrix
Sporotrichosis
Sporotrichosis - diagnosis
Sporotrichosis - drug therapy
Sporotrichosis - epidemiology
Terbinafine
Transmission
Tropical diseases
Vector-borne diseases
Zoonoses
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sporotrichosis is a subcutaneous or implantation mycosis caused by some species of the genus Sporothrix. Rio de Janeiro state, Brazil, experiences hyperendemic levels of zoonotic sporotrichosis, with increasing cases of disseminated disease, especially in people living with HIV (PLHIV). Involvement of the nasal mucosa is rare and occurs isolated or in disseminated cases, with a delayed resolution. This study aimed to describe the epidemiological, clinical, and therapeutic profiles of 37 cases of sporotrichosis with involvement of the nasal mucosa treated at the ear, nose, and throat (ENT) outpatient clinic of the Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, from 1998 to 2020. Data were reviewed from the medical records and stored in a database. The Mann-Whitney test was used to compare the means of quantitative variables, and Pearson chi-square and Fisher's exact tests were used to verify the association between qualitative variables (p
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0011212