Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial

In terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise screening uptake and detection of pre-cancer. This study was co...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2023-06, Vol.18 (6), p.e0286909-e0286909
Main Authors: Fujita, Misuzu, Nagashima, Kengo, Shimazu, Minobu, Suzuki, Misae, Tauchi, Ichiro, Sakuma, Miwa, Yamamoto, Setsuko, Hanaoka, Hideki, Shozu, Makio, Tsuruoka, Nobuhide, Kasai, Tokuzo, Hata, Akira
Format: Article
Language:English
Subjects:
Acceptability
Access to information
Biology and life sciences
Cancer
Cancer screening
Care and treatment
Cellular biology
Cervical cancer
Chi-square test
Clinical trials
Diagnosis
Human papillomavirus
Immunization
Medical screening
Medicine and Health Sciences
Oncology, Experimental
Papillomavirus infections
Papillomaviruses
People and Places
Performance evaluation
Physical Sciences
Prevention
Questionnaires
Regression analysis
Research and Analysis Methods
Sampling
Statistical analysis
Surveys
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3
cites cdi_FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3
container_end_page e0286909
container_issue 6
container_start_page e0286909
container_title PloS one
container_volume 18
creator Fujita, Misuzu
Nagashima, Kengo
Shimazu, Minobu
Suzuki, Misae
Tauchi, Ichiro
Sakuma, Miwa
Yamamoto, Setsuko
Hanaoka, Hideki
Shozu, Makio
Tsuruoka, Nobuhide
Kasai, Tokuzo
Hata, Akira
description In terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise screening uptake and detection of pre-cancer. This study was conducted to explore the acceptability and preference of self-sampling using a subset of the data from this trial. A pre-invitation letter was sent to eligible women, aged 30-59 years who had not undergone cervical cancer screening for three or more years. After excluding those who declined to participate in this trial, the remaining women were assigned to the self-sampling and control groups. A second invitation letter was sent to the former group, and those wanting to undergo the self-sampling test ordered the kit. A self-sampling HPV kit, consent form, and a self-administered questionnaire were sent to participants who ordered the test. Of the 7,340 participants in the self-sampling group, 1,196 (16.3%) administered the test, and 1,192 (99.7%) answered the questionnaire. Acceptability of the test was favorable; 75.3-81.3% of participants agreed with positive impressions (easy, convenient, and clarity of instruction), and 65.1-77.8% disagreed with negative impressions (painful, uncomfortable, and embarrassing). However, only 21.2% were confident in their sampling procedure. Willingness to undergo screening with a self-collected sample was significantly higher than that with a doctor-collected sample (89.3% vs. 49.1%; p
doi_str_mv 10.1371/journal.pone.0286909
format article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2823977395</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A752290326</galeid><doaj_id>oai_doaj_org_article_03df662d520343d2ad8e1d811400342d</doaj_id><sourcerecordid>A752290326</sourcerecordid><originalsourceid>FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3</originalsourceid><addsrcrecordid>eNqNk9Fu0zAUhiMEYmPwBggsISG4aHHsxLG5QVU1oGjSJAbcWieO03py7MxOKvYMvDTO2k0r2gWKpRydfOc_9h-fLHuZ43lOq_zDpR-DAzvvvdNzTDgTWDzKjnNByYwRTB_fi4-yZzFeYlxSztjT7IhWhItK8OPsz0Ip3Q9QG2uGa-RbFLVtZxG63hq3RpuxA4d66I21voOtCWNEg44Dan1ASoetUWCRApdiFFXQ2k11xqFv0IP7iBboaky88c6BCRrFMWz19QQMG40Wy-XpxQUaggH7PHvSgo36xf59kv38fPpj-XV2dv5ltVyczRQTdJg1VVlCXfGiJiWnRJccM5brWoiG57whldAkLc6pqqFlDW8Ya2hdgaKFqFJ4kr3e6fbWR7n3MUrCCRVVRUWZiNWOaDxcyj6YDsK19GDkTcKHtYQwGGW1xLRpGSNNmWwuaEOg4TpPG8kLnBJk6vZp322sO90o7YYA9kD08IszG7n2W5ljUgjOSFJ4t1cI_sZL2ZmotLXgtB9vNl4wXuE8T-ibf9CHj7en1pBOYFzrU2M1icpFVRIiMCUsUfMHqPQ0ujMq3brWpPxBwfuDgsQM-vewhjFGubr4_v_s-a9D9u09dqPBDpvo7TjdqXgIFjtQBR9j0O2dyzmW09DcuiGnoZH7oUllr-7_obui2ymhfwG-xRI3</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2823977395</pqid></control><display><type>article</type><title>Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Fujita, Misuzu ; Nagashima, Kengo ; Shimazu, Minobu ; Suzuki, Misae ; Tauchi, Ichiro ; Sakuma, Miwa ; Yamamoto, Setsuko ; Hanaoka, Hideki ; Shozu, Makio ; Tsuruoka, Nobuhide ; Kasai, Tokuzo ; Hata, Akira</creator><contributor>Du, Ruofei</contributor><creatorcontrib>Fujita, Misuzu ; Nagashima, Kengo ; Shimazu, Minobu ; Suzuki, Misae ; Tauchi, Ichiro ; Sakuma, Miwa ; Yamamoto, Setsuko ; Hanaoka, Hideki ; Shozu, Makio ; Tsuruoka, Nobuhide ; Kasai, Tokuzo ; Hata, Akira ; Du, Ruofei</creatorcontrib><description>In terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise screening uptake and detection of pre-cancer. This study was conducted to explore the acceptability and preference of self-sampling using a subset of the data from this trial. A pre-invitation letter was sent to eligible women, aged 30-59 years who had not undergone cervical cancer screening for three or more years. After excluding those who declined to participate in this trial, the remaining women were assigned to the self-sampling and control groups. A second invitation letter was sent to the former group, and those wanting to undergo the self-sampling test ordered the kit. A self-sampling HPV kit, consent form, and a self-administered questionnaire were sent to participants who ordered the test. Of the 7,340 participants in the self-sampling group, 1,196 (16.3%) administered the test, and 1,192 (99.7%) answered the questionnaire. Acceptability of the test was favorable; 75.3-81.3% of participants agreed with positive impressions (easy, convenient, and clarity of instruction), and 65.1-77.8% disagreed with negative impressions (painful, uncomfortable, and embarrassing). However, only 21.2% were confident in their sampling procedure. Willingness to undergo screening with a self-collected sample was significantly higher than that with a doctor-collected sample (89.3% vs. 49.1%; p&lt;0.001). Willingness to undergo screening with a doctor-collected sample was inversely associated with age and duration without screening (both p&lt;0.001), but that with a self-collected sample was not associated. Among women who used the self-sampling HPV test, high acceptability was confirmed, while concerns about self-sampling procedures remained. Screening with a self-collected sample was preferred over a doctor-collected sample and the former might alleviate disparities in screening rates.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0286909</identifier><identifier>PMID: 37289798</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acceptability ; Access to information ; Biology and life sciences ; Cancer ; Cancer screening ; Care and treatment ; Cellular biology ; Cervical cancer ; Chi-square test ; Clinical trials ; Diagnosis ; Human papillomavirus ; Immunization ; Medical screening ; Medicine and Health Sciences ; Oncology, Experimental ; Papillomavirus infections ; Papillomaviruses ; People and Places ; Performance evaluation ; Physical Sciences ; Prevention ; Questionnaires ; Regression analysis ; Research and Analysis Methods ; Sampling ; Statistical analysis ; Surveys</subject><ispartof>PloS one, 2023-06, Vol.18 (6), p.e0286909-e0286909</ispartof><rights>Copyright: © 2023 Fujita et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Fujita et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Fujita et al 2023 Fujita et al</rights><rights>2023 Fujita et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3</citedby><cites>FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3</cites><orcidid>0000-0001-5308-4744 ; 0000-0003-4529-9045 ; 0000-0002-7247-2205</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2823977395/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2823977395?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25732,27903,27904,36991,36992,44569,53769,53771,74872</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37289798$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Du, Ruofei</contributor><creatorcontrib>Fujita, Misuzu</creatorcontrib><creatorcontrib>Nagashima, Kengo</creatorcontrib><creatorcontrib>Shimazu, Minobu</creatorcontrib><creatorcontrib>Suzuki, Misae</creatorcontrib><creatorcontrib>Tauchi, Ichiro</creatorcontrib><creatorcontrib>Sakuma, Miwa</creatorcontrib><creatorcontrib>Yamamoto, Setsuko</creatorcontrib><creatorcontrib>Hanaoka, Hideki</creatorcontrib><creatorcontrib>Shozu, Makio</creatorcontrib><creatorcontrib>Tsuruoka, Nobuhide</creatorcontrib><creatorcontrib>Kasai, Tokuzo</creatorcontrib><creatorcontrib>Hata, Akira</creatorcontrib><title>Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>In terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise screening uptake and detection of pre-cancer. This study was conducted to explore the acceptability and preference of self-sampling using a subset of the data from this trial. A pre-invitation letter was sent to eligible women, aged 30-59 years who had not undergone cervical cancer screening for three or more years. After excluding those who declined to participate in this trial, the remaining women were assigned to the self-sampling and control groups. A second invitation letter was sent to the former group, and those wanting to undergo the self-sampling test ordered the kit. A self-sampling HPV kit, consent form, and a self-administered questionnaire were sent to participants who ordered the test. Of the 7,340 participants in the self-sampling group, 1,196 (16.3%) administered the test, and 1,192 (99.7%) answered the questionnaire. Acceptability of the test was favorable; 75.3-81.3% of participants agreed with positive impressions (easy, convenient, and clarity of instruction), and 65.1-77.8% disagreed with negative impressions (painful, uncomfortable, and embarrassing). However, only 21.2% were confident in their sampling procedure. Willingness to undergo screening with a self-collected sample was significantly higher than that with a doctor-collected sample (89.3% vs. 49.1%; p&lt;0.001). Willingness to undergo screening with a doctor-collected sample was inversely associated with age and duration without screening (both p&lt;0.001), but that with a self-collected sample was not associated. Among women who used the self-sampling HPV test, high acceptability was confirmed, while concerns about self-sampling procedures remained. Screening with a self-collected sample was preferred over a doctor-collected sample and the former might alleviate disparities in screening rates.</description><subject>Acceptability</subject><subject>Access to information</subject><subject>Biology and life sciences</subject><subject>Cancer</subject><subject>Cancer screening</subject><subject>Care and treatment</subject><subject>Cellular biology</subject><subject>Cervical cancer</subject><subject>Chi-square test</subject><subject>Clinical trials</subject><subject>Diagnosis</subject><subject>Human papillomavirus</subject><subject>Immunization</subject><subject>Medical screening</subject><subject>Medicine and Health Sciences</subject><subject>Oncology, Experimental</subject><subject>Papillomavirus infections</subject><subject>Papillomaviruses</subject><subject>People and Places</subject><subject>Performance evaluation</subject><subject>Physical Sciences</subject><subject>Prevention</subject><subject>Questionnaires</subject><subject>Regression analysis</subject><subject>Research and Analysis Methods</subject><subject>Sampling</subject><subject>Statistical analysis</subject><subject>Surveys</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNk9Fu0zAUhiMEYmPwBggsISG4aHHsxLG5QVU1oGjSJAbcWieO03py7MxOKvYMvDTO2k0r2gWKpRydfOc_9h-fLHuZ43lOq_zDpR-DAzvvvdNzTDgTWDzKjnNByYwRTB_fi4-yZzFeYlxSztjT7IhWhItK8OPsz0Ip3Q9QG2uGa-RbFLVtZxG63hq3RpuxA4d66I21voOtCWNEg44Dan1ASoetUWCRApdiFFXQ2k11xqFv0IP7iBboaky88c6BCRrFMWz19QQMG40Wy-XpxQUaggH7PHvSgo36xf59kv38fPpj-XV2dv5ltVyczRQTdJg1VVlCXfGiJiWnRJccM5brWoiG57whldAkLc6pqqFlDW8Ya2hdgaKFqFJ4kr3e6fbWR7n3MUrCCRVVRUWZiNWOaDxcyj6YDsK19GDkTcKHtYQwGGW1xLRpGSNNmWwuaEOg4TpPG8kLnBJk6vZp322sO90o7YYA9kD08IszG7n2W5ljUgjOSFJ4t1cI_sZL2ZmotLXgtB9vNl4wXuE8T-ibf9CHj7en1pBOYFzrU2M1icpFVRIiMCUsUfMHqPQ0ujMq3brWpPxBwfuDgsQM-vewhjFGubr4_v_s-a9D9u09dqPBDpvo7TjdqXgIFjtQBR9j0O2dyzmW09DcuiGnoZH7oUllr-7_obui2ymhfwG-xRI3</recordid><startdate>20230608</startdate><enddate>20230608</enddate><creator>Fujita, Misuzu</creator><creator>Nagashima, Kengo</creator><creator>Shimazu, Minobu</creator><creator>Suzuki, Misae</creator><creator>Tauchi, Ichiro</creator><creator>Sakuma, Miwa</creator><creator>Yamamoto, Setsuko</creator><creator>Hanaoka, Hideki</creator><creator>Shozu, Makio</creator><creator>Tsuruoka, Nobuhide</creator><creator>Kasai, Tokuzo</creator><creator>Hata, Akira</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-5308-4744</orcidid><orcidid>https://orcid.org/0000-0003-4529-9045</orcidid><orcidid>https://orcid.org/0000-0002-7247-2205</orcidid></search><sort><creationdate>20230608</creationdate><title>Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial</title><author>Fujita, Misuzu ; Nagashima, Kengo ; Shimazu, Minobu ; Suzuki, Misae ; Tauchi, Ichiro ; Sakuma, Miwa ; Yamamoto, Setsuko ; Hanaoka, Hideki ; Shozu, Makio ; Tsuruoka, Nobuhide ; Kasai, Tokuzo ; Hata, Akira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acceptability</topic><topic>Access to information</topic><topic>Biology and life sciences</topic><topic>Cancer</topic><topic>Cancer screening</topic><topic>Care and treatment</topic><topic>Cellular biology</topic><topic>Cervical cancer</topic><topic>Chi-square test</topic><topic>Clinical trials</topic><topic>Diagnosis</topic><topic>Human papillomavirus</topic><topic>Immunization</topic><topic>Medical screening</topic><topic>Medicine and Health Sciences</topic><topic>Oncology, Experimental</topic><topic>Papillomavirus infections</topic><topic>Papillomaviruses</topic><topic>People and Places</topic><topic>Performance evaluation</topic><topic>Physical Sciences</topic><topic>Prevention</topic><topic>Questionnaires</topic><topic>Regression analysis</topic><topic>Research and Analysis Methods</topic><topic>Sampling</topic><topic>Statistical analysis</topic><topic>Surveys</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fujita, Misuzu</creatorcontrib><creatorcontrib>Nagashima, Kengo</creatorcontrib><creatorcontrib>Shimazu, Minobu</creatorcontrib><creatorcontrib>Suzuki, Misae</creatorcontrib><creatorcontrib>Tauchi, Ichiro</creatorcontrib><creatorcontrib>Sakuma, Miwa</creatorcontrib><creatorcontrib>Yamamoto, Setsuko</creatorcontrib><creatorcontrib>Hanaoka, Hideki</creatorcontrib><creatorcontrib>Shozu, Makio</creatorcontrib><creatorcontrib>Tsuruoka, Nobuhide</creatorcontrib><creatorcontrib>Kasai, Tokuzo</creatorcontrib><creatorcontrib>Hata, Akira</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological &amp; Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Meteorological &amp; Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fujita, Misuzu</au><au>Nagashima, Kengo</au><au>Shimazu, Minobu</au><au>Suzuki, Misae</au><au>Tauchi, Ichiro</au><au>Sakuma, Miwa</au><au>Yamamoto, Setsuko</au><au>Hanaoka, Hideki</au><au>Shozu, Makio</au><au>Tsuruoka, Nobuhide</au><au>Kasai, Tokuzo</au><au>Hata, Akira</au><au>Du, Ruofei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2023-06-08</date><risdate>2023</risdate><volume>18</volume><issue>6</issue><spage>e0286909</spage><epage>e0286909</epage><pages>e0286909-e0286909</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>In terms of medical policy for cervical cancer prevention, Japan lags far behind other industrialized countries. We initiated a randomized controlled trial to evaluate the self-sampling human papillomavirus (HPV) test as a tool to raise screening uptake and detection of pre-cancer. This study was conducted to explore the acceptability and preference of self-sampling using a subset of the data from this trial. A pre-invitation letter was sent to eligible women, aged 30-59 years who had not undergone cervical cancer screening for three or more years. After excluding those who declined to participate in this trial, the remaining women were assigned to the self-sampling and control groups. A second invitation letter was sent to the former group, and those wanting to undergo the self-sampling test ordered the kit. A self-sampling HPV kit, consent form, and a self-administered questionnaire were sent to participants who ordered the test. Of the 7,340 participants in the self-sampling group, 1,196 (16.3%) administered the test, and 1,192 (99.7%) answered the questionnaire. Acceptability of the test was favorable; 75.3-81.3% of participants agreed with positive impressions (easy, convenient, and clarity of instruction), and 65.1-77.8% disagreed with negative impressions (painful, uncomfortable, and embarrassing). However, only 21.2% were confident in their sampling procedure. Willingness to undergo screening with a self-collected sample was significantly higher than that with a doctor-collected sample (89.3% vs. 49.1%; p&lt;0.001). Willingness to undergo screening with a doctor-collected sample was inversely associated with age and duration without screening (both p&lt;0.001), but that with a self-collected sample was not associated. Among women who used the self-sampling HPV test, high acceptability was confirmed, while concerns about self-sampling procedures remained. Screening with a self-collected sample was preferred over a doctor-collected sample and the former might alleviate disparities in screening rates.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>37289798</pmid><doi>10.1371/journal.pone.0286909</doi><tpages>e0286909</tpages><orcidid>https://orcid.org/0000-0001-5308-4744</orcidid><orcidid>https://orcid.org/0000-0003-4529-9045</orcidid><orcidid>https://orcid.org/0000-0002-7247-2205</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1932-6203
ispartof PloS one, 2023-06, Vol.18 (6), p.e0286909-e0286909
issn 1932-6203
1932-6203
language eng
recordid cdi_plos_journals_2823977395
source Publicly Available Content Database; PubMed Central
subjects Acceptability
Access to information
Biology and life sciences
Cancer
Cancer screening
Care and treatment
Cellular biology
Cervical cancer
Chi-square test
Clinical trials
Diagnosis
Human papillomavirus
Immunization
Medical screening
Medicine and Health Sciences
Oncology, Experimental
Papillomavirus infections
Papillomaviruses
People and Places
Performance evaluation
Physical Sciences
Prevention
Questionnaires
Regression analysis
Research and Analysis Methods
Sampling
Statistical analysis
Surveys
title Acceptability of self-sampling human papillomavirus test for cervical cancer screening in Japan: A questionnaire survey in the ACCESS trial
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T17%3A53%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Acceptability%20of%20self-sampling%20human%20papillomavirus%20test%20for%20cervical%20cancer%20screening%20in%20Japan:%20A%20questionnaire%20survey%20in%20the%20ACCESS%20trial&rft.jtitle=PloS%20one&rft.au=Fujita,%20Misuzu&rft.date=2023-06-08&rft.volume=18&rft.issue=6&rft.spage=e0286909&rft.epage=e0286909&rft.pages=e0286909-e0286909&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0286909&rft_dat=%3Cgale_plos_%3EA752290326%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c693t-d755ab784b25832e580661eb99d818d279e29e2883cbaf6d8d66d3b7ac34976d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2823977395&rft_id=info:pmid/37289798&rft_galeid=A752290326&rfr_iscdi=true