Influence of different primary surgical techniques on long-term intraocular pressure and medication in glaucoma after congenital cataract surgery

• Published in: PloS one 2023-07, Vol.18 (7), p.e0286318-e0286318
• Main Authors: Strzalkowska, Alicja, Strzalkowski, Piotr, Stingl, Julia V, Pfeiffer, Norbert, Schuster, Alexander K, Hoffmann, Esther M
• Format: Article
• Language: English
• Subjects: Analysis; Biology and Life Sciences; Care and treatment; Cataract; Cataracts; Children; Children & youth; Congenital diseases; Cornea; Drug therapy; Engineering and Technology; Eye surgery; Genetic disorders; Glaucoma; Glaucoma in children; Health aspects; Health care facilities; Intraocular pressure; Medical centers; Medical instruments; Medicine and Health Sciences; Methods; Myopia; Patient outcomes; Patients; Pediatrics; Population; Success; Surgery; Surgical techniques; Transplants & implants; Vision disorders in children
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0286318

To assess long-time results of primary surgical treatment in children with glaucoma after congenital cataract surgery. A retrospective study of 37 eyes from 35 children with glaucoma after congenital cataract surgery, who underwent surgery between 2011 and 2021 at the Childhood Glaucoma Center, University Medical Center Mainz, Germany. Only children, who received a primary glaucoma surgery in our clinic within the given time (n = 25) and had at least one-year follow-up (n = 21), were included in the further analysis. The mean follow-up time was 40.4±35.1 months. The primary outcome was the mean reduction in IOP (in mmHg) from baseline to follow-up visits after the surgery, measured with Perkins tonometry. 8 patients (38%) were treated with probe trabeculotomy (probe TO), 6 (29%) with 360° catheter-assisted trabeculotomy (360° TO) and 7 (33%) with cyclodestructive procedures. IOP was significantly reduced after probe TO and 360° TO after 2 years, from 26.9 mmHg to 17.4 mmHg (p