Prescription of oral antidiabetics in Mexico. A cross-sectional study

In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors as...

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Bibliographic Details
Published in:PloS one 2023-07, Vol.18 (7), p.e0288699-e0288699
Main Authors: Fierro, Inmaculada, Gallardo-Mora, Osiel, Alba-Leonel, Adela, Carvajal, Alfonso, Molina-Guarneros, Juan Arcadio
Format: Article
Language:English
Subjects:
Age
Antidiabetics
Biology and Life Sciences
Blood glucose
Body mass index
Committees
Complications and side effects
Contraindications
Cross-sectional studies
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diagnosis
Dosage and administration
Drugs
Epidemics
Ethics
Evaluation
Hospitals
Hypoglycemic agents
Insulin
Medicine and Health Sciences
Metformin
Morbidity
Mortality
Nutrition assessment
Obesity
Overweight
Patient outcomes
Patients
People and places
Population
Prescription drugs
Prescription writing
Type 2 diabetes
Womens health
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Summary:In 2016 diabetes was declared an epidemic and a health emergency in Mexico. As the rationale of the treatment is to achieve target glycemia levels, the appropriateness of the medications used is important. The aim of this study is to learn the pattern of antidiabetic drug prescription and factors associated with inappropriate prescription in Mexico. A retrospective cross-sectional drug utilization study has been conducted. A randomly selected sample was carefully examined. Out of 3600 clinical records of patients diagnosed with type 2 diabetes mellitus (T2DM), 196 records were revised. As far as control is concerned, 36.7% had their glycemia values in the recommended range. A combination of different antidiabetics was the most common pattern observed (60.7%); the most frequent was that of the association of metformin with whatever oral antidiabetics. Prescriptions were considered as inappropriate in 149 cases (76.0%); younger age and lack of nutritional assessment was significantly related to inappropriate prescription. A trend to use more drugs for treating T2DM has been consistently observed. Despite using so many drugs, most of the patients are not controlled. Avoiding inappropriate prescription by following current guidelines may contribute to a better control and, in turn, decrease morbidity and mortality for this cause.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0288699