Electronic patient-reported outcome (ePRO) application for patients with prostate cancer

• Published in: PloS one 2023-08, Vol.18 (8), p.e0289974-e0289974
• Main Authors: Mohseni, Majid, Ayatollahi, Haleh, Arefpour, Amir Mohammad
• Format: Article
• Language: English
• Subjects: Analysis; Cancer therapies; Care and treatment; Chemotherapy; Clinical outcomes; Communication; Complications; Cryotherapy; Data collection; Diagnosis; Disease; Drug therapy; Electronic records; Endocrine therapy; Medical records; Medical treatment; Medicine and Health Sciences; Palliative care; Patients; Prostate cancer; Quality of life; Questionnaires; Radiation; Radiation therapy; Research and Analysis Methods; Side effects; Smartphones; Surgery; Symptom management; Telemedicine; Urology; Usability; User requirements; User satisfaction; Vasectomy
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0289974

Cancer patients experience different complications and outcomes during or after medical treatments. Electronic reporting of the outcomes by patients is a solution that facilitates communication with physicians and improve patient health status. The aim of this study was to develop a smartphone-based application for electronic reporting of outcomes by patients with prostate cancer. The present research was conducted in 2021 in two phases. In the first phase, initially, users' requirements were identified based on reviewing the related literature, existing applications, and guidelines. Then, a questionnaire was designed and the specialists' opinions about the users' requirements were investigated. The specialties included urologists, hemato-oncologists, uro-oncologists, and radiotherapists (n = 15). In the second phase, the application was designed, and patients with prostate cancer (n = 21) and specialists (n = 10) evaluated it using the post-study system usability questionnaire (PSSUQ). Data were analyzed using descriptive statistics. The findings of the first phase of the research showed that out of 108 data elements and functions proposed for the application, 91 items were found essential by the specialists. Data elements were categorized into the patient data, general complications of prostate cancer and side effects of drug therapy, surgery, chemotherapy, cryotherapy, radiation therapy, and hormone therapy. Necessary functions for the application included presenting a patient care summary, communication between the patient and the specialist, free text explanation for complications and sides effects, generating reports, reminder and alert, completing quality of life questionnaire, and calculating the score for the questionnaire. In the second phase of the research, the application was developed and evaluated. The mean value for user satisfaction was (5.95 ± 0.55) out of 7. The developed application can help to accelerate communication with the specialists. It can improve quality of care, reduce unnecessary treatment visits and side effects, and improve timely data collection for a variety of research purposes. However, further research on the cost-effectiveness and usefulness of the collected data is recommended.