Body mass index trends and its impact of under and overweight on outcome among PLHIV on antiretroviral treatment in rural Tanzania: A prospective cohort study

Increased body weight is an important risk factor for cardiovascular disease and is increasingly reported as a health problem in people living with HIV (PLHIV). There is limited data from rural sub-Saharan Africa, where malnutrition usually presents with both over- and undernutrition. We aimed to de...

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Bibliographic Details
Published in:PloS one 2023-08, Vol.18 (8), p.e0290445-e0290445
Main Authors: Kalinjuma, Aneth Vedastus, Hussey, Hannah, Mollel, Getrud Joseph, Letang, Emilio, Battegay, Manuel, Glass, Tracy R, Paris, Daniel, Vanobberghen, Fiona, Weisser, Maja
Format: Article
Language:English
Subjects:
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Biology and Life Sciences
Blood pressure
Body mass
Body mass index
Body size
Body weight
Cardiovascular diseases
Cohort analysis
Consent
Death
Diagnosis
Education
Health aspects
Health hazards
Health risks
HIV
Human immunodeficiency virus
Integrase
Malnutrition
Medicine and Health Sciences
Missing data
Mortality
Obesity
Overweight
Risk factors
Rural areas
Statistical models
Trends
Tuberculosis
Undernutrition
Underweight
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Summary:Increased body weight is an important risk factor for cardiovascular disease and is increasingly reported as a health problem in people living with HIV (PLHIV). There is limited data from rural sub-Saharan Africa, where malnutrition usually presents with both over- and undernutrition. We aimed to determine the prevalence and risk factors of underweight and overweight/obesity in PLHIV enrolled in a cohort in rural Tanzania before the introduction of integrase inhibitors. This nested study of the prospective Kilombero and Ulanga Antiretroviral Cohort included adults aged [greater than or equal to]19 years initiated on antiretroviral therapy between 01/2013 and 12/2018 with follow-up through 06/2019. Body Mass Index (BMI) was classified as underweight (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0290445