A tale of 2 gasses, 1 regulator, and cholesterol homeostasis

There is a burgeoning appreciation for the wide-ranging effects of carbon dioxide on transcriptional regulation and metabolism. Here, Bolshette and colleagues provide the first link between carbon dioxide and the master transcriptional regulator of cholesterol homeostasis.

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Published in:PLoS biology 2023-11, Vol.21 (11), p.e3002401-e3002401
Main Authors: Fenton, Nicole M, Brown, Andrew J
Format: Article
Language:English
Subjects:
Analysis
Biosynthesis
Carbon dioxide
Cholesterol
Core curriculum
Endoplasmic reticulum
Gene regulation
Homeostasis
Membranes
Metabolism
Physiology
Protein binding
Sterols
Waste products
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description There is a burgeoning appreciation for the wide-ranging effects of carbon dioxide on transcriptional regulation and metabolism. Here, Bolshette and colleagues provide the first link between carbon dioxide and the master transcriptional regulator of cholesterol homeostasis.
doi_str_mv 10.1371/journal.pbio.3002401
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subjects Analysis
Biosynthesis
Carbon dioxide
Cholesterol
Core curriculum
Endoplasmic reticulum
Gene regulation
Homeostasis
Membranes
Metabolism
Physiology
Protein binding
Sterols
Waste products
title A tale of 2 gasses, 1 regulator, and cholesterol homeostasis
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