Exploring the relation between Interleukin-6 and high-sensitive cardiac troponin T in asymptomatic hemodialysis patient: A cross-sectional study

High-sensitive cardiac troponin T (h-cTnT), which serves as a marker for myocardial damage, has also been linked to adverse outcomes in asymptomatic hemodialysis patients. This study aims to explore the correlation between interleukin-6 (IL-6) and h-cTnT in asymptomatic hemodialysis patients to unra...

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Bibliographic Details
Published in:PloS one 2024-01, Vol.19 (1), p.e0296965
Main Authors: Ibrahim, Leen, Yasin, Katreen, Abbas, Leen, Ismael, Yahya, Mousa, Ahmed, Alkarajeh, Mohammad, Hamdan, Zakaria, Nazzal, Zaher
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Age
Albumin
Albumins
Analysis
Angina pectoris
Asymptomatic
Atherosclerosis
Biology and Life Sciences
Cardiovascular diseases
Cardiovascular system
Care and treatment
Chronic kidney failure
Comorbidity
Complications and side effects
Coronary artery disease
Coronary heart disease
Correlation
Cross-sectional studies
Cytokines
Diabetes mellitus
Ethylenediaminetetraacetic acid
Health risks
Heart
Heart attacks
Heart diseases
Hemodialysis
Hemodialysis patients
Hospitals
Hypertension
Inflammation
Interleukin 6
Interleukins
Kidney diseases
Medical records
Medical research
Medicine and Health Sciences
Medicine, Experimental
Morbidity
Mortality
Oxidative stress
Patients
Peritoneal dialysis
Population
Sample size
Software
Statistical analysis
Stroke
Toxins
Transferrin
Transferrins
Troponin
Troponin T
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Summary:High-sensitive cardiac troponin T (h-cTnT), which serves as a marker for myocardial damage, has also been linked to adverse outcomes in asymptomatic hemodialysis patients. This study aims to explore the correlation between interleukin-6 (IL-6) and h-cTnT in asymptomatic hemodialysis patients to unravel the relationship between inflammation and cardiovascular risk. A cross-sectional study involving 81 patients was conducted from November 2022 to March 2023 at An-Najah National University Hospital in Palestine. We gathered clinical data, including comorbidities, and obtained blood samples for measuring IL-6 and h-cTnT levels. We performed statistical analyses, including correlation tests and linear regression, to assess the associations between these variables. The study revealed a notable increase in both h-cTnT and IL-6 levels, and a significant correlation between the two (rho = 0.463, P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0296965