Fat quantification in dual-layer detector spectral CT: How to handle iron overload, varying tube voltage and radiation dose Indices

Opposed to other spectral CT techniques, fat quantification in dual-layer detector CT (dlCT) has only recently been developed. The impact of concomitant iron overload and dlCT-specific protocol settings such as the dose right index (DRI), a measure of image noise and tube current, on dlCT fat quanti...

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Bibliographic Details
Published in:PloS one 2024-05, Vol.19 (5), p.e0302863-e0302863
Main Authors: Molwitz, Isabel, Campbell, Graeme Michael, Knopp, Tobias, Schubert, Niklas, Erley, Jennifer, Löser, Anastassia, Adam, Gerhard, Yamamura, Jin, Fischer, Roland, Ozga, Ann-Kathrin, Szwargulski, Patryk
Format: Article
Language:English
Subjects:
Adipose Tissue - diagnostic imaging
Analysis
Biology and Life Sciences
Computed tomography
Correlation coefficient
Correlation coefficients
CT imaging
Decomposition
Detectors
Deviation
Direct reduced iron
Electric potential
Energy
Humans
Iodine
Iron
Iron - analysis
Iron Overload - diagnostic imaging
Liver
Liver - diagnostic imaging
Liver - metabolism
Liver diseases
Medicine and Health Sciences
Methods
Noise measurement
Overloading
Patients
Phantoms, Imaging
Physical Sciences
Radiation Dosage
Research and Analysis Methods
Tomography, X-Ray Computed - methods
Voltage
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Summary:Opposed to other spectral CT techniques, fat quantification in dual-layer detector CT (dlCT) has only recently been developed. The impact of concomitant iron overload and dlCT-specific protocol settings such as the dose right index (DRI), a measure of image noise and tube current, on dlCT fat quantification was unclear. Further, spectral information became newly available
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0302863