Clinical study on the safety and feasibility of AiWalker-K for lower limbs exercise rehabilitation in children with cerebral palsy

Robotic-assisted gait training (RAGT) devices are effective for children with cerebral palsy (CP). Many RAGT devices have been created and put into clinical rehabilitation treatment. Therefore, we aimed to investigate the safety and feasibility of a new RAGT for children with CP. This study is a cro...

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Published in:PloS one 2024-05, Vol.19 (5), p.e0303517
Main Authors: Zhang, Yi, Hui, Zhichong, Qi, Weihang, Zhang, Jiamei, Wang, Mingmei, Zhu, Dengna
Format: Article
Language:English
Subjects:
Adolescent
Adverse events
Arthralgia
Biology and Life Sciences
Blood Pressure
Brain
Cerebral palsied children
Cerebral palsy
Cerebral Palsy - physiopathology
Cerebral Palsy - rehabilitation
Child
Children
Clinical trials
Combined treatment
Cross-Over Studies
Developmental disabilities
Epilepsy
Exercise therapy
Exercise Therapy - methods
Feasibility
Feasibility Studies
Female
Gait
Gait - physiology
Health services
Heart beat
Heart Rate
Hip joint
Humans
Knee
Lower Extremity - physiopathology
Male
Medical personnel
Medicine and Health Sciences
Nervous system
Pain
Pediatrics
Posture
Rehabilitation
Research and Analysis Methods
Robotics - instrumentation
Robotics - methods
Training
Walking
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Hui, Zhichong
Qi, Weihang
Zhang, Jiamei
Wang, Mingmei
Zhu, Dengna
description Robotic-assisted gait training (RAGT) devices are effective for children with cerebral palsy (CP). Many RAGT devices have been created and put into clinical rehabilitation treatment. Therefore, we aimed to investigate the safety and feasibility of a new RAGT for children with CP. This study is a cross-over design with 23 subjects randomly divided into two groups. The occurrence of adverse events and changes in heart rate and blood pressure were recorded during each AiWalker-K training. Additionally, Gross Motor Function Measure-88 (GMFM-88), Pediatric Balance Scale (PBS), 6 Minutes Walking Test (6MWT), Physiological Cost Index, and Edinburgh Visual Gait Score (EVGS) were used to assess treatment, period, carry-over, and follow-up effects in this study. Adverse events included joint pain, skin pain, and injury. Heart rate and blood pressure were higher with the AiWalker-K compared to the rest (P < 0.05), but remained within safe ranges. After combined treatment with AiWalker-K and routine rehabilitation treatment, significant improvements in 6MWT, GMFM-88 D and E, PBS, and EVGS were observed compared to routine rehabilitation treatment alone (P < 0.05). Under the guidance of experienced medical personnel, AiWalker-K can be used for rehabilitation in children with CP.
doi_str_mv 10.1371/journal.pone.0303517
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After combined treatment with AiWalker-K and routine rehabilitation treatment, significant improvements in 6MWT, GMFM-88 D and E, PBS, and EVGS were observed compared to routine rehabilitation treatment alone (P &lt; 0.05). Under the guidance of experienced medical personnel, AiWalker-K can be used for rehabilitation in children with CP.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>38776339</pmid><doi>10.1371/journal.pone.0303517</doi><tpages>e0303517</tpages><orcidid>https://orcid.org/0000-0003-0632-8958</orcidid><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adverse events
Arthralgia
Biology and Life Sciences
Blood Pressure
Brain
Cerebral palsied children
Cerebral palsy
Cerebral Palsy - physiopathology
Cerebral Palsy - rehabilitation
Child
Children
Clinical trials
Combined treatment
Cross-Over Studies
Developmental disabilities
Epilepsy
Exercise therapy
Exercise Therapy - methods
Feasibility
Feasibility Studies
Female
Gait
Gait - physiology
Health services
Heart beat
Heart Rate
Hip joint
Humans
Knee
Lower Extremity - physiopathology
Male
Medical personnel
Medicine and Health Sciences
Nervous system
Pain
Pediatrics
Posture
Rehabilitation
Research and Analysis Methods
Robotics - instrumentation
Robotics - methods
Training
Walking
title Clinical study on the safety and feasibility of AiWalker-K for lower limbs exercise rehabilitation in children with cerebral palsy
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