Detection of hepatitis viruses in suspected cases of Viral Haemorrhagic Fevers in Nigeria

There have been several Viral Hemorrhagic Fever (VHF) outbreaks in Nigeria which remains a public health concern. Despite the increasing number of suspected cases of VHF due to heightened surveillance activities and growing awareness, only a few cases are laboratory-confirmed to be VHF. Routinely, t...

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Bibliographic Details
Published in:PloS one 2024-06, Vol.19 (6), p.e0305521
Main Authors: Salu, Olumuyiwa Babalola, Akinbamiro, Tomilola Feyikemi, Orenolu, Remilekun Mercy, Ishaya, Onyinye Dorothy, Anyanwu, Roosevelt Amaobichukwu, Vitowanu, Olubunmi Rita, Abdullah, Maryam Abiodun, Olowoyeye, Adenike Hellen, Tijani, Sodiq Olawale, Oyedeji, Kolawole Solomon, Omilabu, Sunday Aremu
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Analysis
Biology and life sciences
Child
Child, Preschool
Coinfection - epidemiology
Coinfection - virology
Dengue fever
Dengue viruses
Female
Fever
Health aspects
Hemorrhagic fever
Hemorrhagic Fevers, Viral - diagnosis
Hemorrhagic Fevers, Viral - epidemiology
Hemorrhagic Fevers, Viral - virology
Hepatitis
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis C virus
Hepatitis Viruses - isolation & purification
Humans
Infant
Lassa fever
Male
Medical research
Medicine and health sciences
Medicine, Experimental
Middle Aged
Morbidity
Mortality
Nigeria
Nigeria - epidemiology
People and Places
Public health
Vector-borne diseases
Viruses
Young Adult
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Summary:There have been several Viral Hemorrhagic Fever (VHF) outbreaks in Nigeria which remains a public health concern. Despite the increasing number of suspected cases of VHF due to heightened surveillance activities and growing awareness, only a few cases are laboratory-confirmed to be VHF. Routinely, these samples are only tested for Lassa virus and Yellow fever virus with occasional testing for Dengue virus when indicated. The aetiology of the disease in these VHF suspected cases in Nigeria which are negative for Lassa, Yellow fever and Dengue viruses remains a puzzle. Since the clinical features exhibited by suspected VHF cases are like other endemic illnesses such as Hepatitis, there is a need to investigate the diversity and co-infections of hepatitis viruses as differentials and possible co-morbidity in suspected cases of VHFs in Nigeria. A total of three hundred and fifty (350) blood samples of 212 (60.6%) males and 138 (39.4%) females, aged
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0305521