Global incidence and mortality of childhood leukemia and its relationship with the Human Development Index

Childhood leukemia (CL) is a major global concern, accounting for 33% of all new cancer cases and 31% of all cancer deaths in children aged 0-14 years. Our study aimed to analyze the global incidence and mortality rates of CL in 2020 and its relationship with the Human Development Index (HDI). In th...

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Bibliographic Details
Published in:PloS one 2024-07, Vol.19 (7), p.e0304354
Main Authors: Mohammadian-Hafshejani, Abdollah, Farber, Irina M, Kheiri, Soleiman
Format: Article
Language:English
Subjects:
Adolescent
Age
Analysis
Biology and Life Sciences
Bone marrow
Cancer
Cancer therapies
Child
Child, Preschool
Childhood
Children
Correlation coefficient
Correlation coefficients
Estimates
Fatalities
Female
Females
Global Health - statistics & numerical data
Health aspects
Health care access
Human Development Index
Humans
Incidence
Industrialized nations
Infant
Infant, Newborn
Leukemia
Leukemia - epidemiology
Leukemia - mortality
Leukemia in children
Male
Males
Medical prognosis
Medicine and Health Sciences
Mortality
Oncology, Experimental
People and Places
Population
Socioeconomic factors
Socioeconomics
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Summary:Childhood leukemia (CL) is a major global concern, accounting for 33% of all new cancer cases and 31% of all cancer deaths in children aged 0-14 years. Our study aimed to analyze the global incidence and mortality rates of CL in 2020 and its relationship with the Human Development Index (HDI). In this ecologic study, we analyzed the 2020 cancer incidence and mortality data for children aged 0-14 years from the GLOBOCAN Project. We calculated the Age-Standardized Incidence Rate (ASIR) and Age-Standardized Mortality Rate (ASMR) of CL per 100,000 individuals. Pearson's correlation coefficient was used to examine the association between childhood leukemia ASIR, ASMR, and the HDI, with a statistical significance threshold of P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0304354