The utilization of the Vezzoni modified Badertscher distension device in breeding programs: Heritability estimates and effect on the hip dysplasia prevalence

Canine hip dysplasia (CHD) is a common orthopedic condition, influenced by both genetic and environmental factors. While current breeding programs often rely on ventrodorsal hip-extended (VDHE) radiographs, it is known they fail to accurately assess hip joint laxity. Therefore additional laxity-orie...

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Bibliographic Details
Published in:PloS one 2024-08, Vol.19 (8), p.e0308984
Main Authors: Deboutte, Birgit, Vandekerckhove, Louis, Stock, Emmelie, Kromhout, Kaatje, Morin, Anthony, Saunders, Jimmy H, Peelman, Luc, Broeckx, Bart J G
Format: Article
Language:English
Subjects:
Animals
Bayes Theorem
Bayesian analysis
Biology and Life Sciences
Breeding
Breeding of animals
Distension
Dogs
Dysplasia
Environmental factors
Estimates
Female
Females
Genotype & phenotype
Guide dogs
Heritability
Hip
Hip dislocation
Hip Dysplasia, Canine - diagnostic imaging
Hip Dysplasia, Canine - epidemiology
Hip Dysplasia, Canine - genetics
Hip joint
Hip Joint - diagnostic imaging
Hip Joint - physiopathology
Joint Instability - epidemiology
Joint Instability - genetics
Joints (anatomy)
Male
Medicine and Health Sciences
Offspring
Orthopedics
Population (statistical)
Prevalence
Statistical methods
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Summary:Canine hip dysplasia (CHD) is a common orthopedic condition, influenced by both genetic and environmental factors. While current breeding programs often rely on ventrodorsal hip-extended (VDHE) radiographs, it is known they fail to accurately assess hip joint laxity. Therefore additional laxity-oriented diagnostic techniques have been developed. This study aims to evaluate the effectiveness of the Vezzoni modified Bädertscher distension device (VMBDD) technique, which quantifies hip joint laxity with the laxity index (LI), as a screening tool in two breeding programs. Data from a Belgian population of assistance dogs (population A) and a French population of guide dogs (population B) were analyzed. The heritability estimates of the LI, estimated using Bayesian statistical methods, were high in both populations (0.83 in population A and 0.82 in population B). Improved screening of parents by combining the VMBDD technique with the VDHE, significantly decreased LI and the prevalence of CHD in their offspring. In population A, when two parents were screened with the VMBDD compared to one, there was an average LI decrease of 0.03 (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0308984