Work intensity and fat mass percentage are associated with asymptomatic morphometric vertebral fractures in knee osteoarthritis patients: A cross-sectional study

Knee osteoarthritis (OA) is a common condition with a prevalence of 365 million individuals globally, and it is an independent risk factor for falls and fractures, notably asymptomatic morphometric vertebral fractures (AMVF). The high prevalence of knee OA, the severity of AMVF, and their combined i...

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Bibliographic Details
Published in:PloS one 2024-09, Vol.19 (9), p.e0308746
Main Authors: Zolkiply, Izzatul Nadiah, Wong, Kah Keng, Mohammad Sallehudin, Hakimah, Bidin, Mohammad Zulkarnain, Che Hamzah, Fahrudin, Bahari, Norafida, Wan Ghazali, Wan Syamimee
Format: Article
Language:English
Subjects:
Aged
Analysis
Asymptomatic
Biology and Life Sciences
Body fat
Body mass index
Care and treatment
Comorbidity
Confidentiality
Cross-Sectional Studies
Data collection
Diabetes
Diabetes mellitus
Diagnosis
Disease prevention
Ethics
Falls (Accidents)
Female
Fractures
Health aspects
Humans
Knee
Male
Medical research
Medicine and Health Sciences
Medicine, Experimental
Metabolism
Middle Aged
Musculoskeletal system
Obesity - complications
Occupations
Orthopedics
Osteoarthritis
Osteoarthritis, Knee - epidemiology
Osteoarthritis, Knee - etiology
Osteoporosis
Patients
Physiological aspects
Quality of life
Questionnaires
Regression analysis
Rheumatology
Risk Factors
Sarcopenia
Sociodemographics
Spinal Fractures - epidemiology
Spinal Fractures - etiology
Variables
Vertebrae
Womens health
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Summary:Knee osteoarthritis (OA) is a common condition with a prevalence of 365 million individuals globally, and it is an independent risk factor for falls and fractures, notably asymptomatic morphometric vertebral fractures (AMVF). The high prevalence of knee OA, the severity of AMVF, and their combined impacts on quality of life underscore the need for early detection, appropriate treatment and management. To address this, our cross-sectional study aims to identify potential predictive factors associated with AMVF in knee OA patients. Our cohort consisted of 76 patients diagnosed with knee OA, predominantly female (84.2%), of Malay ethnicity (84.2%), and obese (55.3%). In univariable analysis, significant association was found between occupation (moderate or heavy work) and AMVF (p
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0308746